Evidence map›Paper›PMID 40205209›Full record

ArticleNature2025

Inhibitory specificity from a connectomic census of mouse visual cortex.

Casey M Schneider-Mizell, Agnes L Bodor, Derrick Brittain, JoAnn Buchanan, Daniel J Bumbarger, Leila Elabbady, Clare Gamlin, Daniel Kapner, Sam Kinn, Gayathri Mahalingam and 31 more

Erratum issuedAbstract read
In one paragraph

Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Cell-Type-Specific Synaptic Scaling Mechanisms Differentially Contribute to Associative Learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  2. Deviance detection via competitive inhibition between local neocortical ensembles.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Article
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  5. Article
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  7. Article
  8. Binocular Circuitry as a Model for Understanding Experience-Dependent Circuit Development across the Mammalian Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Review
  9. Diversity in Whisking-Related Dynamics of Layer 5 Neurons in the Motor Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  10. Article
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  12. Article
  13. Review
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  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

41 authors.

Casey M Schneider-MizellAllen Institute for Brain Science, Seattle, WA, USA. caseys@alleninstitute.org.ORCID 0000-0001-9477-3853
Agnes L BodorAllen Institute for Brain Science, Seattle, WA, USA.
Derrick BrittainAllen Institute for Brain Science, Seattle, WA, USA.
JoAnn BuchananAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-4212-5560
Daniel J BumbargerAllen Institute for Brain Science, Seattle, WA, USA.
Leila ElabbadyAllen Institute for Brain Science, Seattle, WA, USA.
Clare GamlinAllen Institute for Brain Science, Seattle, WA, USA.
Daniel KapnerAllen Institute for Brain Science, Seattle, WA, USA.
Sam KinnAllen Institute for Brain Science, Seattle, WA, USA.
Gayathri MahalingamAllen Institute for Brain Science, Seattle, WA, USA.
Sharmishtaa SeshamaniAllen Institute for Brain Science, Seattle, WA, USA.
Shelby SuckowAllen Institute for Brain Science, Seattle, WA, USA.
Marc TakenoAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-8384-7500
Russel TorresAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-2876-4382
Wenjing YinAllen Institute for Brain Science, Seattle, WA, USA.
Sven DorkenwaldPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
J Alexander BaePrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-4681-6342
Manuel A CastroPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Akhilesh HalageriPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Zhen JiaPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Chris JordanPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Nico KemnitzPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-0260-4532
Kisuk LeeDepartment of Electrical and Computer Engineering, Rice University, Houston, TX, USA.
Kai LiComputer Science Department, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-2095-7024
Ran LuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Thomas MacrinaPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-0622-9338
Eric MitchellPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-7487-1744
Shanka Subhra MondalPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0003-1252-0129
Shang MuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Barak NehoranPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0001-7371-0829
Sergiy PopovychPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
William SilversmithPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Nicholas L TurnerPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
William WongPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Jingpeng WuPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.
Jacob ReimerDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA.
Andreas S ToliasDepartment of Neuroscience, Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-4305-6376
H Sebastian SeungPrinceton Neuroscience Institute, Princeton University, Princeton, NJ, USA.ORCID 0000-0002-8591-6733
R Clay ReidAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-8697-6797
Forrest CollmanAllen Institute for Brain Science, Seattle, WA, USA.ORCID 0000-0002-0280-7022
Nuno Maçarico da CostaAllen Institute for Brain Science, Seattle, WA, USA. nunod@alleninstitute.org.ORCID 0000-0003-2001-4568

Funding

Generation of novel cell type specific mouse genetic toolsU19MH114830 · NIMH · ALLEN INSTITUTE · PI TOLIAS, ANDREAS · 2017 to 2021
$64.7M
VISION RESEARCH CENTERP30EY002520 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Samuel M Wu · 1985 to 2026
$14.8M
Probabilistic coding in cortical populationsR01EY026927 · NEI · BAYLOR COLLEGE OF MEDICINE · PI MA, WEI JI, TOLIAS, ANDREAS · 2017 to 2021
$1.9M
From synapses to genes through morphology: an integrated characterization of cell types based on connectomics and transcriptomics dataRF1MH125932 · NIMH · ALLEN INSTITUTE · PI COLLMAN, FORREST CHRISTIE, MACARICO DA COSTA, NUNO · 2021 to 2021
$1.4M
NEI NIH HHS P30 EY002520NEI NIH HHS R01 EY026927NIMH NIH HHS RF1 MH125932NIMH NIH HHS U19 MH114830
6 · The paper itself

Abstract

Mammalian cortex features a vast diversity of neuronal cell types, each with characteristic anatomical, molecular and functional properties

Indexed as

ConnectomeNeuronsSynapsesVisual CortexVolume Electron MicroscopyAnimalsDatasets as TopicDendritesInterneuronsMaleMiceMicroscopy, Electron, TransmissionNeural Inhibition

Identifiers

PMID40205209
PMCPMC11981935

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.