ArticleNature medicine2025
Genomic census of invasive nontyphoidal Salmonella infections reveals global and local human-to-human transmission.
Article in Nature medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.
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Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Computational paradigms for antimicrobial resistance prediction: integrating multi-omics, structural modeling, and foundation artificial intelligence systems.Briefings in bioinformatics · 2026Pooled it
- Invasive non-typhoidal Salmonella infections in China (1961-2024): a retrospective systematic analysis of multicentre case reports.Journal of global health · 2026Pooled it
- ZoonoticEmerging microbes & infections · 2026Article
- Population structure and antibiotic resistance of Salmonella isolates from diseased poultry in Jiangxi Province, China.Poultry science · 2026Article
- Global genomic surveillance uncovers emergence and spatiotemporal patterns of World Health Organization priority antibiotic resistance in invasive Salmonella.Nature communications · 2026Article
- One Health genomics reveals niche-specific lineage replacement inNational science review · 2026Article
- Molecular epidemiological and genetic variability ofMicrobiology spectrum · 2026Article
- Genomic insights into antimicrobial resistance in ocular pathogens from India.Communications biology · 2026Article
- Distinct genomic trajectory among invasive Salmonella Typhimurium ST313 infections.Nature communications · 2026Article
- Droplet Digital CRISPR for Nucleic Acid Detection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Design and TAG-Assisted Synthesis of the C-Terminal Amidated Antimicrobial Peptide NCBP-1 Derived from a Plant-Derived Noncanonical NCBP and Its Biological Activity.Protein and peptide letters · 2026Article
- Carbapenem-resistantFrontiers in cellular and infection microbiology · 2026Article
- PreventingFrontiers in microbiology · 2026Article
- Harnessing a high-qualityBiosafety and health · 2025Article
- Laboratory epidemiology ofOne health (Amsterdam, Netherlands) · 2025Article
- Illuminating the genomic frontier of invasive non-typhoidal Salmonella infections.Clinical and translational medicine · 2025Article
- WHO Pandemic Agreement: The need for scientific implementation.PLoS pathogens · 2025Article
- Article
- Ecological prevalence and genomic characterization of Salmonella isolated from selected poultry farms in Jiangxi province, China.Poultry science · 2025Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extraintestinal infections caused by Enterobacteriaceae represent a global concern, further exacerbated by the growing prevalence of antimicrobial resistance (AMR). Among these, invasive nontyphoidal Salmonella (iNTS) infections have become increasingly challenging to manage, and their global spread remains poorly understood. Here we compiled 1,115 patient records and generated a comprehensive genomic dataset on iNTS. Age and sex emerged as significant risk factors, with Salmonella Enteritidis identified as a major cause. We observed serovar-specific AMR patterns, with notable resistance to fluoroquinolones and third-generation cephalosporins. A global phylogenomic analysis of Enteritidis revealed three distinct clades, highlighting the accumulation of AMR determinants during its international spread. Importantly, our genomic and transmission analyses suggest that iNTS infections may involve human-to-human transmission, with diarrheal patients acting as potential intermediaries, deviating from typical zoonotic pathways. Collectively, our newly generated cohort and iNTS genomic dataset provide a framework for precise local iNTS burden and underscore emerging transmission trends.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.