ArticleNature2025
Multimodal cell maps as a foundation for structural and functional genomics.
Erratum issuedAbstract read
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Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- HIT-MAP: A scalable approach to multimodal mapping of subcellular organization.Cell reports methods · 2026Article
- Human genetics across levels of biological organization.Nature reviews. Genetics · 2026Review
- Embryonic Phase Transition/Separation on Hepatic Liquid Crystal Droplets Is Essential for Liver Development.Biology · 2026Article
- Synthesizing Mechanistic Hypotheses from Single-Cell Omics via Discretized Feature Attribution and Empirical Language Model Grounding.bioRxiv : the preprint server for biology · 2026Article
- An Atlas of Short Linear Motif-Mediated Human Protein-Protein Interactions.bioRxiv : the preprint server for biology · 2026Article
- What will be the future of computational biology for macromolecules in the era of AI?PLoS computational biology · 2026Article
- Technologies to measure and modulate protein subcellular localization.Nature reviews. Molecular cell biology · 2026Review
- Subcellular localization as a driver of protein function.Nature reviews. Molecular cell biology · 2026Review
- Cell shapes decode molecular phenotypes in image-based spatial proteomics.Cell systems · 2026Article
- Morphology-robust quantification of subcellular organization in complex cells.bioRxiv : the preprint server for biology · 2026Article
- Brieflow: an integrated computational pipeline for high-throughput analysis of optical pooled screening data.Nature communications · 2026Article
- Generative machine learning unlocks the first proteome-wide image of human cells.bioRxiv : the preprint server for biology · 2026Article
- Rethinking bioinformatics in liquid-liquid phase separation: data resources, predictive models, and an event-centric perspective.Briefings in bioinformatics · 2026Review
- A conceptual blueprint for "turning cold to hot" in Osteosarcoma: from TME stratification hypotheses to adaptive therapeutic prospects.Cell communication and signaling : CCS · 2026Review
- Network-based framework for studying etiology and phenotypic diversity in primary ciliopathies.Genome biology · 2026Article
- Medea: An omics AI agent for therapeutic discovery.bioRxiv : the preprint server for biology · 2026Article
- Artificial Intelligence agents for biological research: a survey.Briefings in bioinformatics · 2026Article
- Using Biological Networks to Guide Biomedical Prediction.Methods in molecular biology (Clifton, N.J.) · 2026Article
- A guide to building the matrisome interactome: from computational predictions to experimental validation.The FEBS journal · 2026Review
- RNase MRP subunit composition and role in 40S ribosome biogenesis.Nature structural & molecular biology · 2026Article
Corrections and comments
- Erratum issued
Authors and funding
34 authors.
Leah V Schaffer *Department of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-6339-9141
Mengzhou Hu *Department of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-1571-8029
Gege QianDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-5068-0399
Kyung-Mee MoonDepartment of Biochemistry & Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0003-3796-720X
Abantika PalDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.
Neelesh SoniDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-9333-7491
Andrew P LathamDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0002-9338-7253
Laura Pontano VaitesDepartment of Cell Biology, Harvard Medical School, Boston, MA, USA.
Dorothy TsaiDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-1484-7961
Nicole M MattsonDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Katherine LiconDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Robin BachelderDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0001-7502-2907
Anthony CesnikDepartment of Bioengineering, Stanford University, Palo Alto, CA, USA.ORCID 0000-0002-5326-7134
Ishan GaurDepartment of Bioengineering, Stanford University, Palo Alto, CA, USA.
Trang LeDepartment of Bioengineering, Stanford University, Palo Alto, CA, USA.
William LeineweberDepartment of Bioengineering, Stanford University, Palo Alto, CA, USA.ORCID 0000-0003-3069-398X
Aji PalarDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0001-9357-6970
Ernst PulidoDepartment of Bioengineering, Stanford University, Palo Alto, CA, USA.ORCID 0000-0002-3616-9743
Yue QinDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Xiaoyu ZhaoDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-6081-2196
Christopher ChurasDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Joanna LenkiewiczDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Jing ChenDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Keiichiro OnoDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Dexter PrattDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.ORCID 0000-0002-1471-9513
Peter ZageDepartment of Pediatrics, Division of Hematology-Oncology, University of California San Diego, La Jolla, CA, USA.
Ignacia EcheverriaDepartment of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA, USA.
Andrej SaliDepartment of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, USA.ORCID 0000-0003-0435-6197
J Wade HarperDepartment of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-6944-7236
Steven P GygiDepartment of Cell Biology, Harvard Medical School, Boston, MA, USA.ORCID 0000-0001-7626-0034
Leonard J FosterDepartment of Biochemistry & Molecular Biology, Michael Smith Laboratories, University of British Columbia, Vancouver, British Columbia, Canada.ORCID 0000-0001-8551-4817
Edward L HuttlinDepartment of Cell Biology, Harvard Medical School, Boston, MA, USA. edward_huttlin@hms.harvard.edu.ORCID 0000-0002-1822-1173
Emma LundbergDepartment of Bioengineering, Stanford University, Palo Alto, CA, USA. emmalu@stanford.edu.ORCID 0000-0001-7034-0850
Trey IdekerDepartment of Medicine, University of California San Diego, La Jolla, CA, USA. tideker@ucsd.edu.ORCID 0000-0002-1708-8454
Funding
Bridge2AI: Cell Maps for AI (CM4AI) Data Generation ProjectOT2OD032742 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jean-Christophe Bélisle-Pipon, TIMOTHY W CLARK · 2022 to 2026
$21.5MTR&D Project 4. The Imaging Stage: Multiscale Spatiotemporal Modeling of Macromolecular Systems in Cellular NeighborhoodsP41GM109824 · NIGMS · ROCKEFELLER UNIVERSITY · PI ROUT, MICHAEL P · 2014 to 2023
$18.8MTR&D 3 - Network Guided Machine LearningP41GM103504 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PICO, ALEXANDER R · 2012 to 2024
$17.3MThe Cancer Cell Map Initiative v2.0U54CA274502 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Nevan J Krogan · 2022 to 2026
$14.2MCYTOSCAPE: AN ECOSYSTEM FOR NETWORK GENOMICSU24HG012107 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Jing Chen, PIETER C DORRESTEIN · 2022 to 2026
$6.5MSystematic Exploration of the Human Interactome IVU24HG006673 · NHGRI · HARVARD MEDICAL SCHOOL · PI GYGI, STEVEN P, HARPER, JEFFREY W · 2018 to 2025
$6.0MNDEx - the Network Data Exchange A Network Commons for BiologistsU24CA184427 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PRATT, DEXTER · 2014 to 2021
$5.7MSystematic Exploration of the Human InteractomeU41HG006673 · NHGRI · HARVARD MEDICAL SCHOOL · PI GYGI, STEVEN P · 2012 to 2017
$5.5MIMP: Software for Hybrid Determination of Macromolecular Assembly StructuresR01GM083960 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SALI, ANDREJ · 2008 to 2024
$5.2MThe Network Data Exchange - a Network Commons for BiologistsU24CA269436 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Dexter Pratt · 2023 to 2026
$3.5MA visible machine learning system to discover targeted treatment solutions in cancerK00CA264422 · NCI · BROAD INSTITUTE, INC. · PI Yue Qin · 2023 to 2026
$395kA visible machine learning system to discover targeted treatment solutions in cancerF99CA264422 · NCI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI QIN, YUE · 2021 to 2022
$80kNCI NIH HHS F99 CA264422NCI NIH HHS K00 CA264422NCI NIH HHS U24 CA184427NCI NIH HHS U24 CA269436NCI NIH HHS U54 CA274502NHGRI NIH HHS U24 HG006673NHGRI NIH HHS U24 HG012107NHGRI NIH HHS U41 HG006673NIGMS NIH HHS P41 GM103504NIGMS NIH HHS P41 GM109824NIGMS NIH HHS R01 GM083960NIH HHS OT2 OD032742
Abstract
Human cells consist of a complex hierarchy of components, many of which remain unexplored
Indexed as
GenomicsCell Line, TumorHumansModels, MolecularMutationOsteosarcoma
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What OpenQuestion holds
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.