Evidence map›Paper›PMID 40204986›Full record

ArticleArchives of virology2025

Porcine circovirus type 2 (PCV2) in Brazil in the past 55 years (1967-2022): evolutionary rates and patterns.

I L F Rodrigues, A C M Cruz, A E Souza, F B Knackfuss, C H C Costa, B V Lago, R L Silveira, T X Castro

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

I L F RodriguesDepartment of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Rua Prof. Hernani Melo, 101, Niterói, Rio de Janeiro, 24210-130, Brazil.ORCID http://orcid.org/0000-0002-3250-2385
A C M CruzDepartment of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Rua Prof. Hernani Melo, 101, Niterói, Rio de Janeiro, 24210-130, Brazil.ORCID http://orcid.org/0000-0002-4520-6884
A E SouzaDepartment of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Rua Prof. Hernani Melo, 101, Niterói, Rio de Janeiro, 24210-130, Brazil.ORCID http://orcid.org/0000-0003-2327-3864
F B KnackfussUniversidade do Grande Rio/UNIGRANRIO, School of Health Sciences, Rua Professor José de Souza Herdy, 1160, 25 de Agosto, Duque de Caxias, RJ, 25071-202, Brazil.ORCID http://orcid.org/0000-0003-4560-1339
C H C CostaPathological Anatomy Laboratory, State Center for Research in Animal Health, Agricultiural Research Company of the State of Rio de Janeiro-Pesagro-Rio, Alameda São Boaventura, Niterói, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-3231-5707
B V LagoViral Hepatitis Laboratory, Oswaldo Cruz Foundation, Av Brasil 4365, Rio de Janeiro, Brazil.ORCID http://orcid.org/0000-0002-9173-6309
R L SilveiraDepartment of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Rua Prof. Hernani Melo, 101, Niterói, Rio de Janeiro, 24210-130, Brazil.ORCID http://orcid.org/0000-0001-7876-0761
T X CastroDepartment of Microbiology and Parasitology, Biomedical Institute, Fluminense Federal University, Rua Prof. Hernani Melo, 101, Niterói, Rio de Janeiro, 24210-130, Brazil. txcastro@id.uff.br.ORCID http://orcid.org/0000-0002-2772-6405

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Porcine circovirus type 2 (PCV2) is a common virus that infects pigs. It exhibits marked genetic variability, which is affected by factors such as vaccination and commercial trade. In this study, a retrospective analysis of PCV2 was performed based on molecular characterization, Bayesian inference, and haplotype networks in tissue samples obtained from Brazilian pig herds from 1967 to 2018. A nested PCR targeting a 225-nucleotide fragment of the PCV2 capsid gene was performed, followed by bidirectional sequencing. Out of 178 samples tested, 39 (21.9%) were positive for PCV2. Phylogenetic analysis showed that strains from this study collected before the introduction of a PCV2 vaccine clustered with genotype 2d reference strains. The mean substitution rate was 1.54 × 10

Indexed as

Circoviridae InfectionsCircovirusEvolution, MolecularSwine DiseasesAnimalsBrazilCapsid ProteinsGenetic VariationGenotypeHaplotypesPhylogenyRetrospective StudiesSwineCapsid Proteins

Identifiers

PMID40204986

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.