Evidence map›Paper›PMID 40204977›Full record

ArticleApplied microbiology and biotechnology2025

Identification of protein-degraders in an anaerobic digester by protein stable isotope probing and metagenomics.

Zhe Deng, Jan Struckmann Poulsen, Jeppe Lund Nielsen, David G Weissbrodt, Henri Spanjers, Jules B van Lier

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhe DengDepartment of Water Management, Delft University of Technology, Stevinweg 1, 2628 CN, Delft, Netherlands. z.deng-2@tudelft.nl.ORCID http://orcid.org/0000-0003-3435-6964
Jan Struckmann PoulsenSection for Biotechnology, Department of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, 9220, Aalborg, Denmark.ORCID http://orcid.org/0000-0003-1841-4028
Jeppe Lund NielsenSection for Biotechnology, Department of Chemistry and Bioscience, Aalborg University, Fredrik Bajers Vej 7H, 9220, Aalborg, Denmark.ORCID http://orcid.org/0000-0002-8747-6938
David G WeissbrodtDepartment of Biotechnology, Delft University of Technology, Van Der Maasweg 9, 2629 HZ, Delft, Netherlands.ORCID http://orcid.org/0000-0002-6313-1652
Henri SpanjersDepartment of Water Management, Delft University of Technology, Stevinweg 1, 2628 CN, Delft, Netherlands.ORCID http://orcid.org/0000-0002-9035-9417
Jules B van LierDepartment of Water Management, Delft University of Technology, Stevinweg 1, 2628 CN, Delft, Netherlands.ORCID http://orcid.org/0000-0003-2607-5425

Funding

China Scholarship Council 201708450043
6 · The paper itself

Abstract

Presence of carbohydrates hampers protein degradation in anaerobic digesters. To understand this phenomenon, we used proteogenomics to identify the active protein-degraders in the presence of low and high carbohydrates concentrations. Active metabolic pathways of the identified protein-degraders were investigated using proteomics with

Indexed as

AcinetobacterBioreactorsMetagenomicsProteinsAnaerobiosisBacterial ProteinsCarbon IsotopesGlucoseIsotope LabelingMetabolic Networks and PathwaysProteolysisProteomicsBacterial ProteinsCarbon IsotopesGlucoseProteinsAnaerobic digestionAnaerobic respirationMetagenomicsProtein-degradersProtein stable isotope probing (protein-SIP)

Identifiers

PMID40204977
PMCPMC11982144

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.