ArticleNature materials2025
DNA photofluids show life-like motion.
Article in Nature materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed.
- Decoding Biomolecular Phase Separation: From Physiological Roles to Pathological Mechanisms and Therapeutic Biomaterials Design.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Carbon Dots as Electrostatically Driven Base-Selective Chemical Compilers for Programmable Nucleic Acid Condensation.JACS Au · 2026Article
- Molecular Crowding Stabilizes DNA Coacervate Droplets and Generates Self-Organized Characteristic Patterns.JACS Au · 2026Article
- Spatially Encoded Protocell Network for Non-Cascaded Parallel Biocomputation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Hierarchical Assembly of Multilayer Core-Shell DNA Origami Crystals.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- Bacterial turbulence drives interfacial waves and shape dynamics in phase-separated droplets.Nature communications · 2026Article
- Let There be Light! Light as an Engine and Regulator in Synthetic Cells.Angewandte Chemie (International ed. in English) · 2026Review
- Dynamic DNA Nanomachines for Biosensing and Drug Delivery.Sensors (Basel, Switzerland) · 2026Review
- AIEgen-mediated integration of plain DNA and hydrophobic compounds enabling three-in-one nanosystems for carrier-free delivery.Journal of nanobiotechnology · 2026Article
- Sequence-Modulated Active Tripeptide Condensates for Tandem Catalysis.Angewandte Chemie (International ed. in English) · 2026Article
- Semi-Independent Control of Stability and Mobility in DNA Condensates.Chembiochem : a European journal of chemical biology · 2026Article
- Omega Nucleic Acids (ΩNA), Ultimate Nucleic Acids for Future Technology.Molecules (Basel, Switzerland) · 2026Review
- Ultra-weak photon emission: from oxidative metabolism to DNA-based communication: a review of biochemical, biophysical and quantum biological perspectives.Frontiers in endocrinology · 2026Review
- Remodeling and self-healing of individual amyloid tactoids via multiphoton absorption.Nature communications · 2025Article
- Amorphous-Crystalline Solid Transformation-Induced Self-Actuation of Bending-to-Straightening Behavior via Helical Deformation.Crystal growth & design · 2025Article
- Molecular motor-driven reversible liquid-liquid phase separation of supramolecular assemblies.Nature communications · 2025Article
- DNA Photofluids: An Innovative Breakthrough in Mimicking Cellular Life Behaviors.Research (Washington, D.C.) · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
As active matter, cells exhibit non-equilibrium structures and behaviours such as reconfiguration, motility and division. These capabilities arise from the collective action of biomolecular machines continuously converting photoenergy or chemical energy into mechanical energy. Constructing similar dynamic processes in vitro presents opportunities for developing life-like intelligent soft materials. Here we report an active fluid formed from the liquid-liquid phase separation of photoresponsive DNA nanomachines. The photofluids can orchestrate and amplify nanoscale mechanical movements by orders of magnitude to produce macroscopic cell-like behaviours including elongation, division and rotation. We identify two dissipative processes in the DNA droplets, photoalignment and photofibrillation, which are crucial for harnessing stochastic molecular motions cooperatively. Our results demonstrate an active liquid molecular system that consumes photoenergy to create ordered out-of-equilibrium structures and behaviours. This system may help elucidate the physical principles underlying cooperative motion in active matter and pave the way for developing programmable interactive materials.
Indexed as
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40204968What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.