ArticleScientific reports2025
Dyadic effects of perceived burden and psychological distress on quality of life among Chinese advanced cancer patients and their caregivers.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed.
- A Sexual Health Self-Management Intervention (Psychosexual Educational Partners Program) for Couples With a History of Breast and Gynecological Cancer: Mixed Methods Feasibility Study.JMIR formative research · 2025Trial
- Benefit finding and caregiving burden among primary caregivers of patients with advanced cancer in China: A latent profile analysis.Asia-Pacific journal of oncology nursing · 2026Article
- Association Between Health-Related Quality of Life In Patients with Colorectal Cancer and Their Informal Caregivers.Advances in therapy · 2026Article
- Content Validation of Primary Care Network Assessment Scale for Palliative Care Patients (ARCP) and Clinical Utility in Patients With Advanced Cancer.Scandinavian journal of caring sciences · 2026Article
- Association of Physical Activity with Psychological Distress and Poor Mental Health Days Among Informal Caregivers of Older Adults: Findings from the 2023 BRFSS Caregiver Module.Healthcare (Basel, Switzerland) · 2026Article
- Health-Related Quality of Life and Related Characteristics of Informal Caregivers Providing Home Health Care to Elderly Patients: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2026Article
- Tailored personas for anticipatory grief management among primary family caregivers of patients with advanced lung cancer in China: a qualitative study.Scientific reports · 2026Article
- Anxiety, Depression, and Caregiver Burden Among Family Caregivers of Cancer Survivors.Brain and behavior · 2026Article
- The unseen symptom: A longitudinal qualitative interview study exploring mobility loss in people with advanced cancer.Palliative medicine · 2026Article
- Effect of three-stage fusion nursing intervention the rehabilitation process and psychological stress in patients after gastric cancer surgery.World journal of gastrointestinal surgery · 2025Article
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9 authors.
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Abstract
This study aims to explore the mediating role of psychological distress in the association between perceived burden and quality of life (QoL) in advanced cancer patient-caregiver dyads. 241 dyads in five tertiary hospitals in a province were investigated by using the Edmonton Symptom Assessment System, Zarit Burden Interview, the Patient Health Questionnaire-4, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Core 15 Palliative scores, and the Short Form Health Survey 8. The actor-partner interdependence mediation model (APIMeM), which assesses both individual (actor) and interdependent (partner) effects within dyadic relationships, was employed to analyze how burden and psychological distress interact across dyad members. Analysis was conducted using Mplus v8.0. Regarding the actor effects, the mediating role of psychological distress between perceived burden and QoL was confirmed in advanced cancer patients (B = -0.223, p = 0.001) and their caregivers (B = -0.168, p < 0.001). Regarding the partner effects, there were no significant correlations between caregiver burden and patients' psychological distress (B = 0.015, p = 0.199), patients' QoL (B = 0.113, p = 0.278), or the indirect association of caregiver burden with patients' QoL through psychological distress (B = -0.034, p = 0.259). However, caregivers' psychological distress was positively correlated with patients' symptom burden and mediated the association between patients' symptom burden and caregivers' QoL (B = -0.090, p = 0.001). The study highlights the importance of taking a dyadic perspective in the context of advanced cancer. Dyadic interventions targeting their perceived burden and psychological distress may be beneficial to their QoL.
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