Evidence map›Paper›PMID 40204800›Full record

ArticleScientific reports2025

Exploring the feasibility and effectiveness of a naturalistic family centered intervention to enhance early interactions in toddlers with Down syndrome.

Ana Mendoza-García, Andrés Aparicio, Paulina Sofía Arango, Marcela Tenorio

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana Mendoza-GarcíaDepartamento Interfacultativo de Psicología Evolutiva y de la Educación, Universidad Autónoma de Madrid, Madrid, Spain.
Andrés AparicioMillennium Institute for Care Research (MICARE), Santiago, Chile.
Paulina Sofía ArangoMillennium Institute for Care Research (MICARE), Santiago, Chile.
Marcela TenorioMillennium Institute for Care Research (MICARE), Santiago, Chile. marcela.tenorio@micare.cl.

Funding

Agencia Estatal de Investigación PRE2020--094773Agencia Nacional de Investigación y Desarrollo 1221400European Social Fund Plus PRE2020--094773
6 · The paper itself

Abstract

This study analyses the feasibility and effectiveness of BabyMICARE, a manualised intervention programme aimed at improving the interactions between caregivers and infants and toddlers with Down syndrome. The programme's goal is to enhance caregivers' sensitivity and reduce directivity during early interactions, particularly during play and daily routines. A pre-test and post-test design was used with 40 dyads of infants with Down syndrome and their caregivers, who were divided into a control group (n = 20) and an intervention group (n = 20), based on baseline scores in key interaction subscales. Sessions were conducted over 10 weeks by trained psychologists. Parent-infant interaction was assessed using the MACI coding system, which measures aspects such as sensitive responsiveness, directivity and the level of reciprocity between the parent and the child. The programme showed high feasibility, with a 100% attendance rate but some rescheduling. Caregivers evaluated it positively. The intervention group demonstrated significant improvements in five of eight MACI scales, particularly in sensitive responsiveness and nondirectiveness, while no changes were observed in the control group. The results suggest that BabyMICARE is a feasible and effective intervention for promoting more responsive, less directive interactions, which may be crucial in fostering children's development.

Indexed as

Down SyndromeParent-Child RelationsAdultCaregiversChild DevelopmentChild, PreschoolFeasibility StudiesFemaleHumansInfantMaleParentsDirectivenessDown syndromeEarly interactionsInterventionSensitive responsiveness

Identifiers

PMID40204800
PMCPMC11982383

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.