Evidence map›Paper›PMID 40204526›Full record

ArticleNMR in biomedicine2025

Reproducibility of the Determination of

Narjes Ahmadian, Sarah M Jacobs, Mark Gosselink, Wybe J M van der Kemp, Hans Hoogduin, Anastasia Coppoli, Graeme F Mason, Robin A de Graaf, Helia Norouzizadeh, Chantal Mahon and 9 more

Abstract read
In one paragraph

Article in NMR in biomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Narjes AhmadianCenter for Image Sciences, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID https://orcid.org/0009-0004-2072-031X
Sarah M JacobsCenter for Image Sciences, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID https://orcid.org/0000-0003-0147-9511
Mark GosselinkCenter for Image Sciences, University Medical Center Utrecht, Utrecht, the Netherlands.
Wybe J M van der KempCenter for Image Sciences, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID https://orcid.org/0000-0003-1123-2352
Hans HoogduinCenter for Image Sciences, University Medical Center Utrecht, Utrecht, the Netherlands.
Anastasia CoppoliYale University School of Medicine, New Haven, Connecticut, USA.
Graeme F MasonYale University School of Medicine, New Haven, Connecticut, USA.
Robin A de GraafYale University School of Medicine, New Haven, Connecticut, USA.ORCID https://orcid.org/0000-0002-6570-7010
Helia NorouzizadehMSD (Europe) Inc., Brussels, Belgium.
Chantal MahonMerck & Co. Inc., Rahway, New Jersey, USA.
Pieter van EijsdenNeurosurgery, University Medical Center Utrecht, Utrecht, the Netherlands.
Renger TiessenICON plc, Groningen, the Netherlands.
Dirk CerneusICON plc, Groningen, the Netherlands.
Corin O MillerMerck & Co. Inc., Rahway, New Jersey, USA.
Inge De LepeleireMSD (Europe) Inc., Brussels, Belgium.
Anthony S BasileMerck & Co. Inc., Rahway, New Jersey, USA.
Dennis W J KlompCenter for Image Sciences, University Medical Center Utrecht, Utrecht, the Netherlands.
Jeanine J PrompersCenter for Image Sciences, University Medical Center Utrecht, Utrecht, the Netherlands.ORCID https://orcid.org/0000-0002-4756-4474
Evita C WiegersCenter for Image Sciences, University Medical Center Utrecht, Utrecht, the Netherlands.

Funding

Merck & Co. Inc.
6 · The paper itself

Abstract

Glutamate (Glu) is the major excitatory neurotransmitter in the central nervous system. The measurement of Glu/glutamine (Gln) neurotransmitters in the brain provides valuable insights into the dynamic aspects of neuroenergetics and neurotransmitter cycles and can be accomplished through the detection of

Indexed as

BrainGlucoseGlutamic AcidGlutamineAdultCarbon IsotopesFemaleHumansIsotope LabelingMagnetic Resonance SpectroscopyMaleReproducibility of ResultsCarbon-13Carbon IsotopesGlucoseGlutamic AcidGlutaminecarbon‐13 (13C)glutamate/glutamineselPOCE

Identifiers

PMID40204526
PMCPMC11981885

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.