Evidence map›Paper›PMID 40204438›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2025

A Role for δ Subunit-Containing GABA

Peter M Lambert, Sofia V Salvatore, Xinguo Lu, Hong-Jin Shu, Ann Benz, Nicholas Rensing, Carla M Yuede, Michael Wong, Charles F Zorumski, Steven Mennerick

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. A Non-Classical Neuroactive Steroid Exhibiting Potent, Efficacious GABAbioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. δ-Containing GABAJournal of neurophysiology · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Peter M LambertDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110.ORCID 0000-0001-9427-638X
Sofia V SalvatoreDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110.
Xinguo LuDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110.
Hong-Jin ShuDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110.
Ann BenzDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110.
Nicholas RensingDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110.
Carla M YuedeDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110.
Michael WongDepartment of Neurology, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110.
Charles F ZorumskiDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110.ORCID 0000-0002-9704-5154
Steven MennerickDepartment of Psychiatry, Washington University in St. Louis School of Medicine, St. Louis, Missouri 63110 menneris@wustl.edu.ORCID 0000-0003-0868-0664

Funding

WUIDDRC Supplement-Supporting the health and well-being of children with intellectual and developmental disability during COVID-19 pandemicP50HD103525 · NICHD · WASHINGTON UNIVERSITY · PI JEFFREY D MILBRANDT · 2020 to 2026
$15.5M
Neuroactive steroids as novel psychiatric treatments: mechanistic studiesP50MH122379 · NIMH · WASHINGTON UNIVERSITY · PI COVEY, DOUGLAS F · 2021 to 2025
$12.2M
GABAA RECEPTOR POPULATIONS IN HIPPOCAMPUS AND THALAMUSR01MH123748 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2021 to 2025
$2.4M
MAXIMIZING STUDENT DIVERSITY IN THE BIOMEDICAL SCIENCES AT WASHINGTON UNIVERSITYT32GM148405 · NIGMS · WASHINGTON UNIVERSITY · PI HERMANSTYNE, TRACEY O, SKEATH, JAMES BENJAMIN · 2023 to 2025
$1.7M
Hippocampal circuit mechanisms of neurosteroidsF30MH126548 · NIMH · WASHINGTON UNIVERSITY · PI LAMBERT, PETER MICHAEL · 2021 to 2024
$171k
NICHD NIH HHS P50 HD103525NIGMS NIH HHS T32 GM148405NIMH NIH HHS F30 MH126548NIMH NIH HHS P50 MH122379NIMH NIH HHS R01 MH123748
6 · The paper itself

Abstract

GABA

Indexed as

Cerebral CortexNeuronsParvalbuminsReceptors, GABA-ASleepAnimalsElectroencephalographyFemaleInterneuronsMaleMiceMice, Inbred C57BLMice, KnockoutParvalbuminsReceptors, GABA-AEEGGABAinhibitionparvalbuminsleep

Identifiers

PMID40204438
PMCPMC12079746

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.