Observational studyBMJ open2025
Associations among health-related quality of life, mental resilience and social support in patients early after surgery for osteoporotic vertebral compression fractures: a longitudinal study.
Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Risk Prediction Models for New Vertebral Fracture After Vertebral Augmentation in Elderly Patients with Osteoporotic Vertebral Compression Fractures: A Systematic Review.Healthcare (Basel, Switzerland) · 2026Review
- Association of Psychological Resilience With Health-Related Quality of Life in Patients Undergoing Hip Fracture Surgery.Journal of patient experience · 2026Article
- Spiritual well-being and quality of life in maintenance hemodialysis patients: a latent profile analysis and serial mediation model.Frontiers in psychology · 2026Article
- Effects of modified vertebral bone quality score and paravertebral muscle mass on multiple osteoporotic vertebral compression fractures: a retrospective multicenter cohort study.Journal of orthopaedic surgery and research · 2025Article
- Healthy ageing and psychological resilience among the empty-nest older adults: a cross-sectional survey in China.BMC geriatrics · 2025Article
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Authors and funding
7 authors.
Funding
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Abstract
objectiveThis study aims to explore the profile of health-related quality of life (HRQoL) of postoperative osteoporotic vertebral compression fracture (OVCF) patients through a longitudinal investigation, especially in the early postoperative phase, discern the effect of mental resilience and social support on postoperative HRQoL and further explore the mechanisms by which mental resilience exerts influences on HRQoL.
designThis longitudinal observational study was conducted to examine the HRQoL of OVCF patients during the early postoperative period. Data collection occurred at three distinct time points: baseline assessment on postoperative day 1 (T1), followed by subsequent evaluations at 1 month (T2) and 3 months (T3) postsurgery.
settingZhoupu Hospital, in Shanghai, China.
participantsA total of 155 postoperative OVCF patients completed the baseline survey, with 150 and 140 participants completing the follow-up at T2 and T3. OUTCOME MEASURES: Primary end-point variables were HRQoL, mental resilience and social support. Secondary end-point outcomes included demographic data and disease-related information.
resultsThe baseline data indicated that the average age of participants was 69.6 years, ranging from 53 to 92 years, with females accounting for 69.0%. There was no significant difference in demographic characteristics, such as age, gender and other factors, between the follow-up and the lost (p>0.05). Although the level of HRQoL, mental resilience and social support still remain at relatively lower levels at three separate times, they gradually elevated with time. Both mental resilience (r=0.293, p<0.01) and social support (r=0.257, p<0.01) demonstrated significant positive correlations with HRQoL. Multiple linear regression analysis at T3 identified smoking history (β=-0.137, p<0.001), gender (β=-0.154, p<0.001) and diabetes (β=0.126, p=0.001) as independent factors for postoperative HRQoL. Longitudinal mediation analysis suggests that social support exerted an indirect effect on HRQoL through mental resilience (β=1.017, p<0.001).
conclusionsMental resilience and social support are strongly intertwined with HRQoL of OVCF patients after surgery in the early postoperative stage. Notably, social support exerts its beneficial effects on HRQoL through enhanced mental resilience in this critical postoperative period. Targeted interventions should be implemented to optimise social support networks and cultivate psychological resilience, which may substantially improve postoperative HRQoL outcomes.
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