Evidence map›Paper›PMID 40204226›Full record

ArticleExperimental eye research2025

Oxygen uptake at the ocular surface in diabetic animals is impaired in response to central corneal injury.

Ana M Sandoval-Castellanos, Sun Qin, Li Ma, Fernando Ferreira, Brian Reid, Min Zhao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental eye research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ana M Sandoval-CastellanosDepartment of Ophthalmology & Vision Science, Institute for Regenerative Cures, School of Medicine, University of California, Davis, Davis, California, USA.
Sun QinDepartment of Dermatology, Institute for Regenerative Cures, School of Medicine, University of California, Davis, Davis, California, USA; School of Life Science, Yunnan Normal University, Yunnan, China.
Li MaDepartment of Dermatology, Institute for Regenerative Cures, School of Medicine, University of California, Davis, Davis, California, USA; Skin and Cosmetic Research Department, Shanghai Skin Disease Hospital, Shanghai, China.
Fernando FerreiraDepartment of Dermatology, Institute for Regenerative Cures, School of Medicine, University of California, Davis, Davis, California, USA; Departamento de Biologia, Centro de Biologia Molecular e Ambiental (CBMA), Universidade do Minho, Braga, Portugal.
Brian ReidDepartment of Ophthalmology & Vision Science, Institute for Regenerative Cures, School of Medicine, University of California, Davis, Davis, California, USA; Department of Dermatology, Institute for Regenerative Cures, School of Medicine, University of California, Davis, Davis, California, USA.
Min ZhaoDepartment of Ophthalmology & Vision Science, Institute for Regenerative Cures, School of Medicine, University of California, Davis, Davis, California, USA; Department of Dermatology, Institute for Regenerative Cures, School of Medicine, University of California, Davis, Davis, California, USA. Electronic address: minzhao@ucdavis.edu.

Funding

Molecular Generators at Corneal Wounds Produce and regulate the Wound Electrical SignalsR01EY019101 · NEI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI ZHAO, MIN · 2010 to 2023
$5.2M
Vision Science Training Program: Cornea to CortexT32EY015387 · NEI · UNIVERSITY OF CALIFORNIA DAVIS · PI MARIE E BURNS · 2003 to 2026
$4.8M
NEI NIH HHS R01 EY019101NEI NIH HHS T32 EY015387
6 · The paper itself

Abstract

Poor wound healing is one of the most devastating complications in late-stage diabetic patients. The avascular cornea does not rely on circulation for its oxygen consumption, uptaking it mainly from the atmosphere. Previous studies demonstrated that oxygen uptake (O

Indexed as

CorneaCorneal InjuriesDiabetes Mellitus, ExperimentalOxygenOxygen ConsumptionAnimalsMaleMiceMice, Inbred C57BLWound HealingOxygen(1–7): corneaDiabetesOptical fiber sensorOxygen sensorOxygen uptakeSpatiotemporal profileWound healing

Identifiers

PMID40204226
PMCPMC12182872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.