ArticleJournal of the neurological sciences2025
Characteristics of adults with first-ever stroke vs. recurrent stroke at the university teaching Hospital in Lusaka, Zambia.
Article in Journal of the neurological sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundStroke burden is increasing in sub-Saharan Africa. We studied differences in stroke risk factors, hospital characteristics, and outcomes between adults with first-ever and recurrent stroke in Zambia.
methodsWe retrospectively collected demographics, clinical presentation, medical history, and in-hospital outcomes and at 90-days post-discharge from adults admitted to the University Teaching Hospital in Lusaka, Zambia between October 2018 - March 2019. We compared descriptive statistics between participants with first-ever and recurrent strokes using t-tests for continuous parametric variables, Wilcoxon rank-sum tests for continuous nonparametric variables, and chi-square or Fisher exact tests for categorical variables.
resultsThis stroke cohort (n = 324) consisted of 253 (78 %) patients with first-ever stroke and 71 (22 %) hospitalized with recurrent stroke. Adults with first-ever stroke were younger than individuals with recurrent stroke (58 ± 18 vs 66 ± 14 years, p < 0.001), more likely to present with undiagnosed hypertension (19 % vs. 6 %, p = 0.01), and had higher rates of intracerebral hemorrhage (32 % vs. 15 %, p = 0.03). Adults with recurrent stroke were more likely to have medical comorbidities, including prior diagnosis of hypertension (90 % vs. 77 %, p = 0.02), atrial fibrillation (26 % vs. 6 %, p = 0.01), and had higher rates of aspiration pneumonia (30 % vs. 12 %, p = 0.001). In-hospital mortality did not differ between groups (31 % in recurrent vs. 22 % in first-ever, p = 0.12) but those with recurrent stroke had higher 90-day mortality (59 % vs 36 %, p = 0.001). DISCUSSION: Our findings suggest improvements in both primary and secondary prevention strategies and programs are needed. Improved hypertension screening and diagnosis while developing chronic disease management programs are necessary for stroke prevention.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.