ArticleThe journal of physical chemistry. A2025
Thioflavin T Inspirations: On the Photophysical and Aggregation Properties of Fluorescent Difluoroborates Based on the Benzothiazole Core.
Article in The journal of physical chemistry. A, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Thioflavin-T derivatives with controlled AIE and ACQ properties as potential one-photon and two-photon amyloid markers.Scientific reports · 2026Article
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Authors and funding
5 authors.
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Abstract
In this work, we investigated a novel series of fluorescent dyes based on benzothiazole core substituted with a palette of donor groups that differ in size, shape, and character (alkyl vs aromatic). These dyes exhibit an intramolecular charge transfer state in their electronic structure. The photophysical properties of the newly synthesized dyes were studied with an eye toward aggregation effects in solvents and mixtures of solvents differing in polarity. Moreover, multiphoton absorption studies were performed to determine the potential of the dyes in two-photon microscopy. The results of spectroscopic measurements were supported by electronic structure calculations using coupled-cluster theory. Overall, the results provide an indication regarding the optimal substituents to achieve bright emission in various media and how these properties are related to aggregation effects.
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Registered trials
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