Evidence map›Paper›PMID 40203118›Full record

ArticleScience advances2025

Silicate-based therapy for inflammatory dilated cardiomyopathy by inhibiting the vicious cycle of immune inflammation via FOXO signaling.

Ping Sun, Zhaowenbin Zhang, Fei Gao, Chen Yang, Ge Mang, Shuai Fu, Jiawei Tian, Jiang Chang

Abstract read
In one paragraph

Article in Science advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Nanomaterials-Based Immunotherapy for Atherosclerosis.Small (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  2. Review
  3. Article
  4. Research progress on the mechanism of FOXO protein in sepsis.Apoptosis : an international journal on programmed cell death · 2026
    Review
  5. Review
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ping SunDepartment of Ultrasound, The Second Affiliated Hospital of Harbin Medical University, Harbin 1500086, China.ORCID 0000-0002-5487-9503
Zhaowenbin ZhangJoint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID 0000-0003-0682-8354
Fei GaoDepartment of Ultrasound, The Second Affiliated Hospital of Harbin Medical University, Harbin 1500086, China.ORCID 0000-0001-7389-1973
Chen YangJoint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID 0000-0001-9820-1692
Ge MangThe Key Laboratory of Myocardial Ischemia, Ministry of Education, Harbin Medical University, Harbin 150086, China.ORCID 0000-0003-3953-7000
Shuai FuDepartment of Ultrasound, The Second Affiliated Hospital of Harbin Medical University, Harbin 1500086, China.ORCID 0000-0002-4192-5259
Jiawei TianDepartment of Ultrasound, The Second Affiliated Hospital of Harbin Medical University, Harbin 1500086, China.ORCID 0000-0001-6674-8714
Jiang ChangJoint Centre of Translational Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.ORCID 0000-0003-1462-6541

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory dilated cardiomyopathy (iDCM) represents a severe immune-related condition provoked by the progression of myocarditis. In patients suffering from myocarditis, a vicious cycle of inflammation orchestrated by CD4

Indexed as

Cardiomyopathy, DilatedForkhead Box Protein O1Forkhead Box Protein O3InflammationSignal TransductionSilicatesAnimalsFibroblastsHumansMaleMiceMyocardiumNeutrophilsTh17 CellsForkhead Box Protein O1Forkhead Box Protein O3Silicates

Identifiers

PMID40203118
PMCPMC11980853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.