Observational studyJournal of nephrology2025
Early-stage chronic kidney disease as a risk factor for suicide: a nationwide observational cohort study.
Observational study in Journal of nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Association of health screening participation with cardiovascular mortality and suicide in patients with schizophrenia and bipolar disorder.Social psychiatry and psychiatric epidemiology · 2026Article
- Holistic needs assessment for hospitalized patients with kidney disease: a prospective cross-sectional study.Journal of nephrology · 2025Article
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Authors and funding
14 authors.
Funding
Abstract
backgroundChronic kidney disease (CKD) is associated with poor psychological well-being. Whether early-stage CKD is a risk factor for suicide warrants further research.
methodsThis nationwide, retrospective, cohort study aimed to evaluate the risk of suicide in patients with early-stage CKD and identify the associated risk factors. A total of 3.945,198 individuals aged ≥ 19 years who underwent the 2009 national health screening in South Korea were studied. Among them, 202,291 patients had early-stage CKD (estimated glomerular filtration rate (eGFR) ≥ 30 and < 60 mL/min per 1.73 m
resultsThe study population had a mean age of 59 ± 15 years, and 47% were male. We identified 930 suicides (incidence rate, 0.45 per 1000 person-years) in the CKD group and 11,332 suicides (incidence rate, 0.27 per 1000 person-years) in the non-CKD group. Early-stage CKD was significantly associated with an increased risk of suicide in multivariable analysis adjusted for demographic characteristics; lifestyle habits; comorbidities, including diabetes and hypertension; economic status; and depression, bipolar disorder, schizophrenia (hazard ratio, 1.18; 95% confidence interval 1.10‒1.26). Suicide incidence was higher in individuals with proteinuria but preserved kidney function (eGFR > 60 mL/min per 1.73 m
conclusionHealthcare providers may need to examine the mental health of patients with early-stage CKD to prevent suicide.
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