Evidence map›Paper›PMID 40202672›Full record

ReviewNaunyn-Schmiedeberg's archives of pharmacology2025

Comprehensive insights into pancreatic cancer treatment approaches and cutting-edge nanocarrier solutions: from pathology to nanomedicine.

Rohit Sharma, Sourabh Kumar, Kumari Komal, Rashmi Ghosh, Shubham Thakur, Ravi Raj Pal, Manish Kumar

Abstract readReview
PubMed Publisher
In one paragraph

Review in Naunyn-Schmiedeberg's archives of pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rohit SharmaDepartment of Pharmaceutics, ISF College Pharmacy, GT Road, Moga, 142001, Punjab, India.
Sourabh KumarDepartment of Pharmaceutics, ISF College Pharmacy, GT Road, Moga, 142001, Punjab, India.
Kumari KomalDepartment of Pharmaceutics, ISF College Pharmacy, GT Road, Moga, 142001, Punjab, India.
Rashmi GhoshDepartment of Pharmaceutics, ISF College Pharmacy, GT Road, Moga, 142001, Punjab, India.
Shubham ThakurDepartment of Pharmaceutics, ISF College Pharmacy, GT Road, Moga, 142001, Punjab, India.
Ravi Raj PalDepartment of Pharmaceutics, ISF College Pharmacy, GT Road, Moga, 142001, Punjab, India.
Manish KumarDepartment of Pharmaceutics, ISF College Pharmacy, GT Road, Moga, 142001, Punjab, India. manish_singh17@rediffmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer is one of the most lethal malignancies worldwide. It is characterized by poor prognosis, high mortality, and recurrence rates. Various modifiable and non-modifiable risk factors are associated with pancreatic cancer incidence. Available treatments for pancreatic cancer include surgery, chemotherapy, radiotherapy, photodynamic therapy, supportive care, targeted therapy, and immunotherapy. However, the survival rates for PC are very low. Regrettably, despite efforts to enhance prognosis, the survival rate of pancreatic cancer remains relatively low. Therefore, it is essential to investigate new approaches to improve pancreatic cancer treatment. By synthesizing current knowledge and identifying existing gaps, this article provides a comprehensive overview of risk factors, pathology, conventional treatments, targeted therapies, and recent advancements in nanocarriers for its treatment, along with various clinical trials and patents that justify the safety and efficacy of innovative carriers for drug delivery systems. Ultimately, this review underscores the potential of these innovative formulations to improve outcomes and contribute significantly to the advancement of Pancreatic Cancer treatment. Together, these insights highlight nano-formulations as a promising frontier for effectively treating Pancreatic Cancer.

Indexed as

Antineoplastic AgentsDrug CarriersNanomedicineNanoparticlesPancreatic NeoplasmsAnimalsDrug Delivery SystemsHumansAntineoplastic AgentsDrug CarriersActive targetingChemotherapyLiposomeNanocarriersNanoparticlesPancreasPancreatic cancer

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.