Evidence map›Paper›PMID 40202557›Full record

ReviewCurrent neurology and neuroscience reports2025

Neurological Manifestations Associated with Exercise at Altitude.

A Marengo, M Tejada, I Hancco Zirena, S Molina

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A MarengoServicio de Neurología. Hospital Perrupato, San Martin, Mendoza, Argentina. dra.andreamarengo@gmail.com.ORCID http://orcid.org/0000-0002-6080-5738
M TejadaUnidad de Cuidados Críticos, Hospital Santa Caterina, Girona, España. malenactejada@gmail.com.
I Hancco ZirenaFacultad de Medicina Humana, Centro de Investigación en Medicina de Altura (CIMA), Universidad de San Martín de Porres, Lima, Perú.
S MolinaPsg Medicina Urgencia en Montaña, Diplomatura Medicina de Urgencia en Montaña EUCS-Universidad nacional de San Juan, San Juan, Argentina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThe effects that exercise at altitude has on the neurological system are diverse and still not well studied, and range from metabolic adaptations to modification of cerebral blood flow and neurotransmitters. In this review we summarise changes with exercise intensity, the implications of ascent, cognitive impairment, psychosis-like symptoms, the role of exercise in the development and prevention of AMS, and use of free radical scavengers to enhance sports performance and acclimatization. RECENT

findingsWe discuss the impact of oxidative stress in hypobaric hypoxia and reactive oxygen species (ROS) production and its consequences, with special focus on exercise at altitude. Finally we consider how moderate intensity exercise could help prevent AMS, and the necessity of research on high intensity exercise with elevated rate of ascent, the development of specific tools of cognitive assessment, and the role of free-radical scavengers in the prevention of AMS and neurological symptoms.

Indexed as

AltitudeAltitude SicknessExerciseNervous System DiseasesHumansHypoxiaOxidative StressReactive Oxygen SpeciesReactive Oxygen SpeciesCognitiveExerciseHigh-altitude illnessHypoxiaNeurologicalOxidative stress

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.