ArticleJournal of the American Chemical Society2025
Direct Observation of Alkyl Group Transmetalation from Boron to Copper: Impact of Structure Modification and the Critical Role of Copper-Oxygen Preassociation in Stereospecificity.
Article in Journal of the American Chemical Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Ligand-modulated metal-radical polarity match enables general 1,2-dicarbofunctionalization of ethylene.Nature chemistry · 2026Article
- Article
- From Boron to Bismuth: The Pre-transmetalation Complex in the Aryl Transfer.Journal of the American Chemical Society · 2026Article
- Vicinal Stereocenter Construction via α-Boryl Carbanions from Borylated Cyclopropanes.Journal of the American Chemical Society · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
Mechanistic investigations of prospective intermediates in copper-catalyzed cross-coupling reactions with alkyllithium-activated alkylboronic esters are described. Complexes between (NHC)copper and the borate salts were characterized by X-ray crystallography and NMR, and the rate of intramolecular transmetalation of an alkyl group from boron to copper was measured. Derived activation parameters were correlated with those determined by DFT analysis and give insight into the mechanism of stereospecific transmetalation.
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Registered trials
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