Evidence map›Paper›PMID 40202373›Full record

ArticleAlimentary pharmacology & therapeutics2025

Immigration Factors and Monitoring of Chronic Hepatitis B Infection Among Foreign-Born: The FOCUS-HBV Multicentre Cohort.

Kali Zhou, Ariel Lee, Christopher Wong, Amol S Rangnekar, Ariana Chen, James Ajokubi, Andrea I Keller, Coleman I Smith, Asif A Hitawala, Maria Mironova and 6 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Alimentary pharmacology & therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Kali ZhouDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Ariel LeeDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Christopher WongDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Amol S RangnekarMedstar Georgetown Transplant Institute, Washington, DC, USA.
Ariana ChenUniversity of Michigan, Ann Arbor, Michigan, USA.
James AjokubiMedstar Georgetown Transplant Institute, Washington, DC, USA.
Andrea I KellerMedstar Georgetown Transplant Institute, Washington, DC, USA.
Coleman I SmithMedstar Georgetown Transplant Institute, Washington, DC, USA.
Asif A HitawalaLiver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0002-2888-0172
Maria MironovaLiver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Harish GopalakrishnaLiver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Jaha Norman-WheelerLiver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Marc G GhanyLiver Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.ORCID https://orcid.org/0000-0003-2837-0188
Jennifer L DodgeDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Norah A TerraultDepartment of Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Christine C HsuMedstar Georgetown Transplant Institute, Washington, DC, USA.

Funding

Multilevel Determinants of Socioeconomic Disparities in Geographic Late Stage Hepatocellular Carcinoma HotspotsK23MD016963 · NIMHD · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Kali Zhou · 2022 to 2026
$829k
Gilead SciencesNIDDK NIH HHSNIMHD NIH HHS 5K23MD016963NIMHD NIH HHS K23 MD016963
6 · The paper itself

Abstract

backgroundImmigrants are the largest subgroup living with chronic hepatitis B (HBV) infection in the United States. It is not well understood how immigration and associated social and cultural factors impact adherence to HBV monitoring.

methodsWe conducted a multicentre multilingual survey among foreign-born adults with chronic HBV between 7/2021 and 4/2023. Participants were surveyed regarding (1) immigration factors, (2) acculturation and language preferences, (3) social determinants of health and (4) HBV-related clinical factors. The primary outcome was optimal adherence, defined as 100% of the time with at least annual testing of HBV DNA, ALT and ultrasound while under care. Logistic regression was used to examine survey factors associated with the outcome.

resultsTwo hundred and seventy-four foreign-born patients with HBV (median 57 years, 57% male) from 32 birth countries were included. Thirteen per cent had immigrated within the past 10 years, and 62% were US citizens. Nearly all (92%) reported seeing a specialist for HBV, with 72% currently on treatment. 44% of participants had optimal adherence to monitoring over a median of 6 years (2-7) under care. Factors associated with more optimal adherence on multivariate testing included non-English survey language (OR 2.32, 95% CI 1.15-4.66), non-US citizens (OR 2.05, 95% CI 1.01-4.15) and higher education (college vs. high school or less: OR 2.39, 95% CI 1.09-5.24). Medicare insurance (vs. private) was associated with less optimal adherence (OR 0.42, 95% CI 0.19-0.94).

conclusionAdherence to long-term monitoring is suboptimal among a diverse cohort of immigrants with chronic HBV. More efforts to engage and retain immigrants in care are needed.

Indexed as

Emigrants and ImmigrantsHepatitis B, ChronicAcculturationAdultAgedCohort StudiesFemaleHumansMaleMiddle AgedSurveys and QuestionnairesUnited Statescare cascadeimmigrant healthsocial determinants of healthviral hepatitis

Identifiers

PMID40202373
PMCPMC12970947

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.