Evidence map›Paper›PMID 40202098›Full record

ArticleNeurogastroenterology and motility2026

Defining Pharyngeal and Upper Esophageal Sphincter Disorders on High-Resolution Manometry-Impedance: The Leuven Consensus.

Taher I Omari, Julia C F Maclean, Charles Cock, Timothy M McCulloch, Nogah Nativ-Zeltzer, Ashli K O'Rourke, Michal M Szczesniak, Peter I Wu, Jacqueline Allen, Yoichiro Aoyagi and 16 more

Registry-linked trialAbstract read
In one paragraph

Article in Neurogastroenterology and motility, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07365046 (Comprehensive Analysis of the Swallowing Mechanism Using High-resolution Manometry With Impedance), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07365046 nanot yet recruitingnot on this map

Comprehensive Analysis of the Swallowing Mechanism Using High-resolution Manometry With Impedance

TypeinterventionalSponsorUniversity Hospital OstravaRan2026 to 2028Enrolled160ConditionsExtraesophageal Reflux, Laryngopharyngeal Reflux, Dysphagia, Chronic CoughArmsHigh resolution oesophageal manometry with impedance, 24-hour pH metry
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. What the "Voices" of Dysphagia Are Thinking about Its Future.International archives of otorhinolaryngology · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Taher I OmariCollege of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0001-5108-7378
Julia C F MacleanSt George & Sutherland Clinical School, UNSW Medicine, Sydney, Australia.ORCID https://orcid.org/0000-0002-9326-2792
Charles CockDepartment of Gastroenterology & Hepatology, Flinders Medical Centre, Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0003-3578-1137
Timothy M McCullochSurgery-Otolaryngology Head & Neck Surgery, University of Wisconsin-Madison, Madison, USA.
Nogah Nativ-ZeltzerFaculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID https://orcid.org/0000-0003-1511-5321
Ashli K O'RourkeDepartment of Otolaryngology, Medical University of South Carolina, Charleston, South Carolina, USA.ORCID https://orcid.org/0000-0002-1293-501X
Michal M SzczesniakSt George & Sutherland Clinical School, UNSW Medicine, Sydney, Australia.ORCID https://orcid.org/0000-0002-9812-8373
Peter I WuUniversity of New South Wales, Sydney, Australia.ORCID https://orcid.org/0000-0001-8137-9179
Jacqueline AllenDepartment of Surgery, University of Auckland, Auckland, New Zealand.ORCID https://orcid.org/0000-0002-3302-7045
Yoichiro AoyagiDepartment of Rehabilitation Medicine, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.ORCID https://orcid.org/0000-0003-0544-325X
Howell Henrian G BayonaGraduate School of Health Sciences, Fujita Health University, Aichi, Japan.ORCID https://orcid.org/0000-0002-7885-2452
Silvia CarriónGastrointestinal Physiology Laboratory, Hospital de Mataró, Consorci Sanitari del Maresme, Mataró, Spain.ORCID https://orcid.org/0000-0002-1354-2488
Michelle R CiucciSurgery-Otolaryngology Head & Neck Surgery, University of Wisconsin-Madison, Madison, USA.
Kate DavidsonDepartment of Otolaryngology, Medical University of South Carolina, Charleston, South Carolina, USA.
Shumon I DharDepartment of Otolaryngology-Head & Neck Surgery, Division of Laryngology, UT Southwestern Medical Center, Dallas, USA.ORCID https://orcid.org/0000-0001-9873-8641
Shaheen HamdySchool of Medical Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0001-9640-7427
Rebecca HowellUniversity of Cincinnati Medical Centre, Cincinnati, USA.ORCID https://orcid.org/0000-0002-5503-0325
Corrine JonesSpeech, Language, & Hearing Sciences, Moody College of Communication, the University of Texas, Austin, USA.
Molly A KniggeUW Health System, Madison, USA.
An MoonenDepartment of Gastroenterology and Hepatology, UZ Leuven, Leuven, Belgium.
Gregory N PostmaDepartment of Otolaryngology, Medical College of Georgia at Augusta University, Augusta, USA.
Jo Puntil-SheltmanSt.George Regional, Hospital/Intermountain Health, St. George, USA.
Anais RameauSean Parker Institute for the Voice, Department of Otolaryngology - Head and Neck Surgery, Weill Cornell Medicine, New York, New York, USA.
Julie ReganDepartment of Clinical Speech & Language Studies, Trinity College Dublin, Dublin, Ireland.
Mistyka ScharDepartment of Gastroenterology & Hepatology, Flinders Medical Centre, Adelaide, South Australia, Australia.ORCID https://orcid.org/0000-0002-7440-592X
Nathalie RommelUniversity of Leuven, Faculty of Medicine, Dept Neurosciences, Experimental Otorhinolaryngology, Deglutology, Leuven, Belgium.ORCID https://orcid.org/0000-0001-5675-7334

Funding

Dr Falk Pharma provided an unrestricted educational grantLaborie Medical Technologies
6 · The paper itself

Abstract

introductionThe Leuven Consensus provides a classification scheme for the diagnosis of pharyngeal and upper esophageal sphincter (UES) motor disorders using metrics derived from pharyngeal high-resolution manometry-impedance (P-HRM-I).

methodsTwenty-six experts with broad multidisciplinary backgrounds contributed their knowledge and experience to this initiative via a formal deliberative Delphi process. Guidance on a swallow assessment protocol as well as diagnostic criteria for UES dysfunction and pharyngeal contractile dysfunction is provided.

resultsFor UES dysfunction, the stepwise evaluation of UES and intrabolus pressure metrics under increasing bolus volume and/or viscosity conditions is used to confirm failure of manometric relaxation and opening of the UES region. For pharyngeal contractile dysfunction, the evaluation of contractile metrics is used to define pharyngeal hypocontractility or hypercontractility.

conclusionThese recommendations complement routine instrumental investigations and provide a standardized process, criteria, and nomenclature for P-HRM-I assessment of patients reporting symptoms of oropharyngeal dysphagia.

Indexed as

Deglutition DisordersEsophageal Motility DisordersEsophageal Sphincter, UpperManometryConsensusElectric ImpedanceHumansconsensus guidelinedeglutitiondeglutition disordersdiagnosisdysphagiahigh‐resolution manometryintraluminal impedanceprotocol

Identifiers

PMID40202098
PMCPMC13121872

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.