ArticleCureus2025
Metachronous Isolated Splenic Metastasis From Cervical Squamous Cell Carcinoma Directly Invading the Stomach: A Case Report.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Early detection and management strategies for isolated splenic metastasis in cervical cancer: a case report.Frontiers in oncology · 2025Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The spleen is a very rare location for isolated blood-borne metastasis from squamous cell carcinoma of the uterine cervix (cSCC), thus splenic metastases from cSCC are associated with diagnostic and therapeutic challenges. We present a case of a 47-year-old woman with a history of International Federation of Gynecology and Obstetrics (FIGO) stage IIIc, human papillomavirus (HPV)-associated cSCC who presented with an isolated splenic metastasis eight months after completing primary treatment. The patient presented to the emergency department with symptomatic anemia. A CT scan of the abdomen showed a large splenic mass measuring 6.8 x 6.8 cm that appeared to directly invade the fundus of the stomach; a subsequent gastroscopy revealed an ulcerated, oozing lesion, which was biopsied and confirmed to be SCC. Following a multidisciplinary tumor board discussion, given the inability to obtain endoscopic hemostasis, the patient underwent expedited splenectomy, distal pancreatectomy, longitudinal gastrectomy, and pyloroplasty. Histological examination showed a high-grade, HPV-associated cSCC, consistent with metastatic spread from the known primary cervical cancer. The patient was initiated on cisplatin, paclitaxel, and pembrolizumab and received four cycles before experiencing disease progression.
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