ArticleOpen veterinary journal2025
Acute phase proteins as potent early biomarkers for the detection of
Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Recently, an increase in the synthesis of acute phase proteins (APPs) was associated with acute infections and inflammation in rabbits. Aim: The purpose of this study was to identify biochemical and molecular markers in rabbits that could be used for the early diagnosis of diarrhea. Method: Fifty male White New Zealand rabbits with an average weight of 450-650 g and an age of 6-8 weeks were chosen and then divided into two groups: group A, which served as a control and was not exposed to any infections, and group B, which was infected with Results: The results revealed a significant increase in HP, CRP concentration, and CP activity in all infected rabbits. Electrophoresis patterns indicated a decline in serum albumin levels and an increase in α2, β, and γ-globulins levels post-infection. The mRNA expression of HP was significantly increased in infected rabbits. Conclusion: APP patterns and concentrations could be used as potent markers for the early detection of enteric disorders and diarrhea induced by
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