Evidence map›Paper›PMID 40201834›Full record

ArticleOpen veterinary journal2025

Effect of cinnamon oil (

Budiastuti Budiastuti, Naomi Lan Noviana Thesia, Hani Plumeriastuti, Mustofa Helmi Effendi, Emmanuel Nnabuike Ugbo, Aswin Rafif Khairullah, Ikechukwu Benjamin Moses, Katty Hendriana Priscilia Riwu, Riza Zainuddin Ahmad, Sheila Marty Yanestria and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Open veterinary journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Budiastuti BudiastutiStudy Program of Pharmacy Science, Faculty of Health Science, Universitas Muhammadiyah Surabaya, Surabaya, Indonesia.
Naomi Lan Noviana ThesiaMaster Program of Veterinary Science and Public Health, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Hani PlumeriastutiStudy Program of Pharmacy Science, Faculty of Health Science, Universitas Muhammadiyah Surabaya, Surabaya, Indonesia.
Mustofa Helmi EffendiDivision of Veterinary Public Health, Faculty of Veterinary Medicine, Universitas Airlangga, Surabaya, Indonesia.
Emmanuel Nnabuike UgboDepartment of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria.
Aswin Rafif KhairullahResearch Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Ikechukwu Benjamin MosesDepartment of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki, Nigeria.
Katty Hendriana Priscilia RiwuDepartment of Veterinary Public Health, Faculty of Veterinary Medicine, Universitas Pendidikan Mandalika, Mataram, Indonesia.
Riza Zainuddin AhmadResearch Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Sheila Marty YanestriaFaculty of Veterinary Medicine, Universitas Wijaya Kusuma Surabaya, Surabaya, Indonesia.
Wasito WasitoResearch Center for Veterinary Science, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Bima Putra PratamaStudy Program of Pharmacy Science, Faculty of Health Science, Universitas Muhammadiyah Surabaya, Surabaya, Indonesia.
Mo AwwanahResearch Center for Applied Botany, National Research and Innovation Agency (BRIN), Bogor, Indonesia.
Agung PrasetyoResearch Center for Estate Crops, National Research and Innovation Agency (BRIN), Bogor, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic systemic disease known as diabetes mellitus is defined by elevated blood glucose levels and problems with fat, carbohydrate, and protein metabolism. In Indonesia, the cinnamon species found include Aim: The antidiabetic activity of cinnamon essential oil ( Methods: STZ (45 mg/kg BW) was administered intraperitoneally as a single dose. Twenty male rats were employed in this investigation. The rats were divided into five groups: treatment 1 (P1) was administered with STZ and provided with 100 mg/kg BW; treatment 2 (P2) was administered with STZ and provided with 200 mg/kg BW; and treatment 3 (P3) was administered with STZ and provided with 400 mg/kg BW. The negative control group (K-) was not treated with STZ and was treated with 1% Tween 80. For 14 days, the medication was administered daily. Results: The essential oil of cinnamon may lessen glomerulosclerosis, tubular necrosis, tubular degeneration, and glomerular necrosis. The kidney P3 treatment (400 mg/kg BW) produced negligible effects. Conclusion: It is possible to create cinnamon essential oil as an herbal antidiabetic medication by lowering the degree of kidney cell damage.

Indexed as

CinnamomumDiabetes Mellitus, ExperimentalHypoglycemic AgentsKidneyOils, VolatileAnimalsCinnamomum zeylanicumMaleRatsRats, WistarStreptozocinHypoglycemic AgentsOils, VolatileStreptozocinAntidiabeticCinnamomum burmanniiEssential oilKidneyStreptozotocin

Identifiers

PMID40201834
PMCPMC11974283

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.