Evidence map›Paper›PMID 40201725›Full record

ArticleOpen forum infectious diseases2025

Whole Genome Sequencing Analysis of

Federico Becerra-Aparicio, Silvia Gómez-Zorrilla, Marta Hernández-García, Kyriaki Xanthopoulou, Desiré Gijón, Ana Siverio, Dàmaris Berbel, Emilia Cercenado, Alba Rivera, Ana De Malet and 14 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Federico Becerra-AparicioServicio de Microbiología, Hospital Universitario Ramón y Cajal-IRYCIS, Madrid, Spain.ORCID https://orcid.org/0000-0002-0948-0958
Silvia Gómez-ZorrillaServicio de Enfermedades Infecciosas, Hospital del Mar-IMIM, Barcelona, Spain.ORCID https://orcid.org/0000-0002-5987-068X
Marta Hernández-GarcíaServicio de Microbiología, Hospital Universitario Ramón y Cajal-IRYCIS, Madrid, Spain.
Kyriaki XanthopoulouInstitute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0001-8591-8184
Desiré GijónServicio de Microbiología, Hospital Universitario Ramón y Cajal-IRYCIS, Madrid, Spain.
Ana SiverioServicio de Enfermedades Infecciosas, Hospital del Mar-IMIM, Barcelona, Spain.
Dàmaris BerbelServicio de Microbiología, Hospital de Bellvitge, Barcelona, Spain.
Emilia CercenadoServicio de Microbiología, Hospital Gregorio Marañón, Madrid, Spain.
Alba RiveraServicio de Microbiología, Hospital Santa Creu i San Pau, Barcelona, Spain.ORCID https://orcid.org/0000-0002-9709-6162
Ana De MaletServicio de Microbiología, Hospital Universitario Lucus Augusti, Lugo, Spain.
Mariona XercavinsMicrobiología-CATLAB, Hospital Universitari Mútua Terrassa, Barcelona, Spain.ORCID https://orcid.org/0000-0003-1463-6344
Enrique Ruiz De GopeguiCIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain.
Luis Canoura-FernándezDepartamento de Microbiología, Complexo Hospitalario de Pontevedra, Pontevedra, Spain.
José Antonio MartínezServicio de Enfermedades Infecciosas, Hospital Clinic, Barcelona, Spain.
Cristina SeralCIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain.
José Luis Del PozoServicio de Microbiología, Clínica Universitaria de Navarra, Pamplona, Spain.
Manuel CotareloDepartamento Médico, MSD Spain, Madrid, Spain.ORCID https://orcid.org/0000-0002-7017-0369
Ricardo PonzDepartamento Médico, MSD Spain, Madrid, Spain.ORCID https://orcid.org/0009-0007-9027-3326
Paul G HigginsInstitute for Medical Microbiology, Immunology and Hygiene, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.ORCID https://orcid.org/0000-0001-8677-9454
Xavier Durán-JordàMethodology and Biostatistics Support Unit, Institut Hospital del Mar d'Investigacions Mèdiques, Barcelona, Spain.
Rafael CantónServicio de Microbiología, Hospital Universitario Ramón y Cajal-IRYCIS, Madrid, Spain.ORCID https://orcid.org/0000-0003-1675-3173
Antonio OliverCIBER de Enfermedades Infecciosas, Instituto de Salud Carlos III, Madrid, Spain.
Juan Pablo HorcajadaServicio de Enfermedades Infecciosas, Hospital del Mar-IMIM, Barcelona, Spain.
Patricia Ruiz-GarbajosaServicio de Microbiología, Hospital Universitario Ramón y Cajal-IRYCIS, Madrid, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The objective of this study was to assess the microbiological and clinical features of Methods: A total of 96 (21.4%, 96/449) Results: 3GCR-Kp prevalence was 43.8% (42/96), mostly associated with extended-spectrum β-lactamase production (34/96, 35.4%; mainly CTX-M-15, 32/34, 94.1%) and the dissemination of sequence type (ST)-307 (15/34, 44.1%) and other globally spread multidrug-resistant high-risk clones. CR-Kp prevalence was 9.4% (9/96); all isolates belonged to different STs and were mostly associated with carbapenemase production (6/9, 66.7%; mainly OXA-48-like, n = 3). Additionally, 3GCR-Kp and CR-Kp isolates showed higher content of other antibiotic resistance genes. Altogether, these episodes were associated with prior antibiotic use and receipt of inadequate empirical treatment. Conclusions: There is a high prevalence of 3GCR and

Indexed as

carbapenemase-producing Enterobacteralesextended-spectrum β-lactamaseshealth care–associated infectionsKlebsiella pneumoniaeST307 clone

Identifiers

PMID40201725
PMCPMC11977326

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.