Evidence map›Paper›PMID 40201667›Full record

ArticleHeart rhythm O22025

Effectiveness of cryoballoon ablation for atrial fibrillation in patients with left common pulmonary vein variant.

Adi Elias, Ibrahim Marai, Alon Eyal, Wisam Darawsha, Faheem Shehadeh, Robert Glueck, Roy Beinart, Eyal Nof, Yoav Michowitz, Michael Glikson and 7 more

Abstract read
In one paragraph

Article in Heart rhythm O2, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Adi EliasCardiac Electrophysiology and Pacing, Eyal Ofer Heart Hospital, Rambam Health Care Campus, Haifa, Israel.
Ibrahim MaraiCardiology Department, Baruch Padeh Medical Center, Azrieli Faculty of Medicine in the Galilee, Bar-Ilan University, Safed, Israel.
Alon EyalCardiac Electrophysiology and Pacing, Eyal Ofer Heart Hospital, Rambam Health Care Campus, Haifa, Israel.
Wisam DarawshaCardiac Electrophysiology and Pacing, Eyal Ofer Heart Hospital, Rambam Health Care Campus, Haifa, Israel.
Faheem ShehadehCardiac Electrophysiology and Pacing, Eyal Ofer Heart Hospital, Rambam Health Care Campus, Haifa, Israel.
Robert GlueckCardiac Electrophysiology and Pacing, Eyal Ofer Heart Hospital, Rambam Health Care Campus, Haifa, Israel.
Roy BeinartHeart Institute, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Ramat Gan, Israel.
Eyal NofHeart Institute, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Ramat Gan, Israel.
Yoav MichowitzJesselson Integrated Heart Center, Shaare Zedek Medical Center, Hebrew University, Jerusalem, Israel.
Michael GliksonJesselson Integrated Heart Center, Shaare Zedek Medical Center, Hebrew University, Jerusalem, Israel.
Yuval KonstantinoDepartment of Cardiology, Cardiac Electrophysiology and Pacing, Soroka University Hospital, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Moti HaimDepartment of Cardiology, Cardiac Electrophysiology and Pacing, Soroka University Hospital, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
David LuriaDepartment of Cardiology, Hadassah Medical Organization, Faculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Alexander OmelchenkoCardiology Department, Meir Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Kfar Saba, Israel.
Avishag Laish-FarkashDepartment of Cardiology, Electrophysiology and Pacing Unit, Assuta Ashdod University Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Mahmoud SuleimanCardiac Electrophysiology and Pacing, Eyal Ofer Heart Hospital, Rambam Health Care Campus, Haifa, Israel.
Israeli Working Group on Pacing and Electrophysiology

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Pulmonary vein isolation (PVI) with cryoballoon technology is widely used for rhythm control in atrial fibrillation (AF). However, there are limited data on its effectiveness in patients with the left common pulmonary vein (LCPV) variant. Objective: The study aimed to examine the outcomes of cryoballoon ablation in patients with the LCPV variant. Methods: The Israeli Catheter Ablation Registry is a prospective, multicenter cohort that included citizens who underwent PVI during the years 2019-2021. Study endpoints were acute isolation success of the pulmonary veins (PVs), AF recurrence, and the need for a repeat ablation procedure at 12 months. Results: The study included 74 patients with the LCPV variant and 822 patients with standard PV anatomy. The acute isolation success rate of the LPVs was significantly lower in LCPV variant patients compared with those with a standard anatomy. However, there was no significant difference in the acute isolation success rate of the right PVs between the 2 groups. At 12 months, the rates of AF recurrence did not differ significantly between the LCPV variant group (17.6%) and the standard anatomy group (11.1%) ( Conclusion: In our study, we found that isolating the LCPV using cryoballoon PVI was more challenging than isolating standard anatomy. Despite this, the effectiveness of cryoballoon ablation in patients with LCPV anatomy did not differ significantly from that in the standard anatomy group.

Indexed as

AnatomyAtrial fibrillationCatheter ablationLeft common pulmonary veinPulmonary vein isolation

Identifiers

PMID40201667
PMCPMC11973657

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.