A cross-sectional study on the association between major dietary pattern and impaired fasting glucose.

Background: Impaired fasting glucose (IFG) is a precursor to type 2 diabetes and is influenced by dietary factors. This cross-sectional study assessed the association between major dietary patterns and IFG in the baseline phase of PERSIAN Kavar cohort study (PKCS). Methods: The study included 3,144 participants aged 35-70 years. After assessing dietary intakes by a food frequency questionnaire, principal component analysis was used to identify dietary patterns. Logistic regression model was applied to estimate the odds ratios (ORs) and 95% confidence intervals (CIs) for the association between dietary patterns and IFG. Results: Three major dietary patterns were identified: healthy, Western-like, and CarnFat (Carnivorous-fat). In the fully adjusted model, individuals in the highest tertile of the healthy dietary pattern had a lower likelihood of IFG compared to those in the lowest tertile (OR = 0.68, 95% CI: 0.53-0.88). The second tertile of the healthy pattern was also associated with lower odds of IFG (OR = 0.77, 95% CI: 0.62-0.96). No significant associations were found for the Western-like and CarnFat dietary patterns. Conclusion: A healthy dietary pattern characterized by high intakes of fruits, vegetables, low-fat dairy, nuts, seeds, olive oil, legumes, fish, and whole grains was associated with a lower risk of IFG. These findings highlight the importance of promoting healthy dietary patterns for the prevention of prediabetes and type 2 diabetes.