Renin-secreting chromophobe renal cell carcinoma: An uncommon cause of secondary hypertension in a young female.

Tareq Jarrar, Younes Jafar Hamam, Hadeel Abdallah Al Kayed, Bassel Esmat Alrabadi, Ayham Kamel Milhem, Maryam Hisham Alqatawna, Husam Odaibat

Abstract readCase Reports

PubMed Full text at PMC Publisher

In one paragraph

Article in Urology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Resolution of Refractory Hypertension Following Radical Nephrectomy for Renal Cell Carcinoma: A Case Report from Somalia in Resource Limit Setting.Cancer management and research · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Tareq JarrarAl-Quds University, Jerusalem, Palestine.

Younes Jafar HamamUniversity of Jordan, Amman, Jordan.

Hadeel Abdallah Al KayedAl Bashir Hospital, Amman, Jordan.

Bassel Esmat AlrabadiJordan University of Science and Technology, Irbid, Jordan.

Ayham Kamel MilhemYarmouk University, Irbid, Jordan.

Maryam Hisham AlqatawnaJordanian Royal Medical Services, Amman, Jordan.

Husam OdaibatJordanian Royal Medical Services, Amman, Jordan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is a rare but significant cause of secondary hypertension. Chromophobe RCC represents 5 % of all RCC cases, with renin secretion being even rarer. We report a case of a 32-year-old female with six-month history of uncontrolled hypertension. Laboratory findings showed elevated plasma renin and aldosterone levels. Imaging revealed a large left renal mass. After radical nephrectomy, histopathology confirmed chromophobe RCC. Her blood pressure normalized postoperatively, and she was normotensive at 1-month follow-up. This case underscores the importance of considering renal tumors in hypertensive patients and the role of surgery in achieving favorable outcomes.

Indexed as

Chromophobe RCCParaneoplastic syndromeRenal cell carcinoma (RCC)Renin-secreting tumorSecondary hypertensionUncontrolled hypertension

Identifiers

PMID40201448

DOI10.1016/j.eucr.2025.103011

PMCPMC11978363

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.