Evidence map›Paper›PMID 40201410›Full record

ArticleBioinorganic chemistry and applications2025

Schiff Bases From 4-Aminoantipyrine: Investigation of Their In Silico, Antimicrobial, and Anticancer Effects and Their Use in Glucose Biosensor Design.

Aşkın Erbaş, Selinsu Dikim, Fatma Arslan, Onur Can Bodur, Seza Arslan, Fatma Özdemir, Nurşen Sarı

Abstract read
In one paragraph

Article in Bioinorganic chemistry and applications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Aşkın ErbaşGraduate School of Natural and Applied Sciences, Gazi University, Ankara, Türkiye.ORCID https://orcid.org/0000-0002-6813-596X
Selinsu DikimDepartment of Chemistry, Faculty of Arts and Science, Kutahya Dumlupinar University, Kutahya, Türkiye.ORCID https://orcid.org/0000-0003-2487-9585
Fatma ArslanDepartment of Chemistry, Faculty of Science, Gazi University, Ankara, Türkiye.ORCID https://orcid.org/0000-0002-3282-6451
Onur Can BodurDepartment of Chemistry, Faculty of Science, Gazi University, Ankara, Türkiye.ORCID https://orcid.org/0000-0001-8915-3078
Seza ArslanDepartment of Biology, Faculty of Arts and Sciences, Bolu Abant Izzet Baysal University, Bolu, Türkiye.ORCID https://orcid.org/0000-0002-2478-6875
Fatma ÖzdemirDepartment of Biology, Faculty of Arts and Sciences, Bolu Abant Izzet Baysal University, Bolu, Türkiye.ORCID https://orcid.org/0000-0002-4804-936X
Nurşen SarıDepartment of Chemistry, Faculty of Science, Gazi University, Ankara, Türkiye.ORCID https://orcid.org/0000-0002-4764-7747

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Five new Schiff bases from 4-aminoantipyrine were synthesized, characterized, and evaluated for their antimicrobial and DNA cleavage activities, and drug similarity properties and cytotoxicity prediction using in silico analysis. All Schiff bases had good antibacterial and antifungal activities. All compounds showed self-activating DNA cleavage ability in the absence of any reductant or oxidant at low concentrations. Modified carbon paste electrodes were prepared with all Schiff bases, and a glucose biosensor was designed. Schiff base coded (4AA-Fc) was found to have the best sensitivity to H

Indexed as

4-aminoantipyrineantimicrobial activitybiosensorDNA cleavageglucosein silico

Identifiers

PMID40201410
PMCPMC11978478

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.