Evidence map›Paper›PMID 40201188›Full record

ArticleFrontiers in neuroscience2025

Use of nasal mucosal autonomic nerve response in efficacy evaluation of vidian neurectomy for allergic rhinitis: a prospective study.

Linzheng Liu, Na Ma, Yan Niu, Yuping Peng, Yan Li, Jiangjiang Shen, Jiameng He, Jindi Sun

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Linzheng Liu *Department of Otolaryngology Head and Neck Surgery, Yulin City First Hospital of Yan'an University, Yulin, China.
Na Ma *Department of Otolaryngology Head and Neck Surgery, Yulin City First Hospital of Yan'an University, Yulin, China.
Yan NiuDepartment of Otolaryngology Head and Neck Surgery, Yulin City First Hospital of Yan'an University, Yulin, China.
Yuping PengDepartment of Otolaryngology Head and Neck Surgery, Yulin City First Hospital of Yan'an University, Yulin, China.
Yan LiDepartment of Otolaryngology Head and Neck Surgery, Yulin City First Hospital of Yan'an University, Yulin, China.
Jiangjiang ShenDepartment of Otolaryngology Head and Neck Surgery, Yulin City First Hospital of Yan'an University, Yulin, China.
Jiameng HeDepartment of Otolaryngology Head and Neck Surgery, Yan'an University, Yan'an, China.
Jindi SunDepartment of Otolaryngology Head and Neck Surgery, Yan'an University, Yan'an, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the use of nasal mucosal autonomic nerve responses as an objective indicator for assessing the efficacy of vidian neurectomy (VN) in treating allergic rhinitis (AR). Methods: Thirty-five patients with moderate to severe AR and 35 healthy controls were included. Autonomic nerve responses were measured before and 1 month after VN surgery, using respiratory stimulation on the nasal mucosa and the opisthenar area. Three waveform types (P-type, N-type and M-type) were identified. Results: While three waveform types were identified in the nasal mucosa, only the M-type was observed in the opisthenar sympathetic skin response. Preoperative measurements showed higher autonomic responses in patients with AR compared with controls. Following VN, the responses in patients with AR decreased significantly, aligning closely with the control group. No significant changes were observed in the opisthenar responses, indicating a localised effect of VN. Comorbidities such as nasal polyps, sinusitis and deviated septum did not impact the results. Conclusion: Nasal mucosal autonomic nerve response provides a reliable, objective measure for evaluating the effectiveness of VN in treating AR.

Indexed as

allergic rhinitisnasal mucosal autonomic nerve responsesympathetic skin responsevidian nervewaveform

Identifiers

PMID40201188
PMCPMC11975872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.