Evidence map›Paper›PMID 40201034›Full record

ArticleOncology letters2025

Achieving stringent complete remission in relapsed/refractory multiple myeloma with liver extramedullary disease after CAR‑T cell therapy: A case report.

Lingyun Zhou, Danbo Liu, Fang Du, Jiao Chen, Wenyi Lu, Hongxian Xiang, Haifei Chen

Abstract readCase Reports
In one paragraph

Article in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lingyun ZhouDepartment of Hematology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong 518000, P.R. China.
Danbo LiuDepartment of Hematology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong 518000, P.R. China.
Fang DuDepartment of Hematology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong 518000, P.R. China.
Jiao ChenDepartment of Hematology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong 518000, P.R. China.
Wenyi LuDepartment of Hematology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong 518000, P.R. China.
Hongxian XiangDepartment of Hematology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong 518000, P.R. China.
Haifei ChenDepartment of Hematology, Shenzhen Luohu People's Hospital, Shenzhen, Guangdong 518000, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple myeloma (MM) is a clonal plasma cell malignancy characterized by bone marrow infiltration and the presence of monoclonal proteins in the blood and urine. However, despite the advances that have been made in terms of its treatment, relapsed/refractory MM (RRMM) remains a significant challenge. Chimeric antigen receptor (CAR)-T cell therapy, which involves the engineering of T-cells to express CARs targeting specific antigens on tumor cells, has emerged as a promising therapeutic approach for RRMM. The present case report presents a patient with RRMM with liver extramedullary disease (EMD) who achieved stringent complete remission following CAR-T cell therapy. This case report highlights the efficacy of CAR-T cell therapy in treating RRMM, also discussing the patient's clinical course, treatment outcomes and side effects, and moreover, a review of the literature that focuses on the treatment of EMD using CAR-T cell therapy.

Indexed as

chimeric antigen receptor T cell therapycytokine release syndromeextramedullary diseasemultiple myelomarelapsed/refractory multiple myelomastringent complete remission

Identifiers

PMID40201034
PMCPMC11977452

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.