Evidence map›Paper›PMID 40200959›Full record

ArticleDEN open2025

Visibility evaluation of gastric epithelial neoplasm of fundic gland mucosa lineage using texture and color enhancement imaging.

Hisanori Utsunomiya, Hiroya Ueyama, Tsutomu Takeda, Shunsuke Nakamura, Yasuko Uemura, Tomoyo Iwano, Momoko Yamamoto, Ryota Uchida, Daiki Abe, Shotaro Oki and 8 more

Abstract read
In one paragraph

Article in DEN open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Hisanori UtsunomiyaDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0001-9408-4628
Hiroya UeyamaDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-5370-1009
Tsutomu TakedaDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Shunsuke NakamuraDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Yasuko UemuraDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Tomoyo IwanoDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Momoko YamamotoDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-9388-1788
Ryota UchidaDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0002-5809-0059
Daiki AbeDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Shotaro OkiDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Nobuyuki SuzukiDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Atsushi IkedaDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Yoichi AkazawaDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.ORCID https://orcid.org/0000-0001-9343-5262
Kumiko UedaDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Mariko HojoDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.
Shuko NojiriMedical Technology Innovation Center Juntendo University School of Medicine Tokyo Japan.
Takashi YaoDepartment of Human Pathology Juntendo University Graduate School of Medicine Tokyo Japan.
Akihito NagaharaDepartment of Gastroenterology Juntendo University School of Medicine Tokyo Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Recently, the incidence of Helicobacter pylori-uninfected gastric cancers, such as gastric epithelial neoplasm of fundic-gland mucosa lineage (GEN-FGML), has increased with the widespread use of eradication therapy. Because the detection and endoscopic diagnosis of GEN-FGML are difficult, an effective observation method in screening endoscopy is required. We investigated whether texture and color enhancement imaging (TXI) improved the visibility of GEN-FGML compared with white light imaging (WLI). Methods: In this single-center prospective clinical study, 50 GEN-FGML lesions (35 patients) treated at our hospital between October 2020 and June 2023 were analyzed. The endoscopic images of GEN-FGML obtained using WLI, TXI mode 1 (TXI-1), TXI mode 2 (TXI-2), and narrow-band imaging were compared by 10 endoscopists. We analyzed the visibility score and inter-rater reliability (intraclass correlation coefficient and conducted an objective evaluation based on Results: Histologically, GEN-FGML was classified as gastric adenocarcinoma of fundic-gland type ( Conclusions: TXI improved the visibility of GEN-FGML for all endoscopists compared with WLI when evaluated subjectively and objectively.

Indexed as

gastric adenocarcinoma of fundic‐gland mucosa typegastric adenocarcinoma of fundic‐gland typegastric epithelial neoplasm of fundic‐gland mucosa lineageoxyntic gland adenomatexture and color enhancement imaging

Identifiers

PMID40200959
PMCPMC11977659

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.