ArticleJournal of pain research2025
Herpes Zoster in Pregnancy: Clinical Outcomes and Treatment Patterns from a Multicenter Retrospective Cohort.
Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Current advances in the epidemiology, risk factors, prevention, management, and long-term outcomes of herpes zoster and post-herpetic neuralgia.Frontiers in microbiology · 2026Pooled it
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Herpes zoster is a global health issue that can lead to complications like neuropathic pain and is particularly risky for those with weakened immune systems. Pregnant women, who experience natural immunosuppression, may face more severe symptoms or longer recovery. However, there is limited data on how herpes zoster affects pregnant women and their babies, especially in Asian populations. Aim: This multicenter study evaluates herpes zoster outcomes and treatment patterns in Chinese pregnant women. Methods: This retrospective multicenter study analyzed real-world data from the Big Data Center at PLA General Hospital, examining medical records of pregnant women with herpes zoster from January 1, 2010, to June 30, 2024, across four hospitals. We gathered patient demographics, herpes zoster details, and pregnancy and delivery information, followed by descriptive statistical analysis. Results: In this study, 72 pregnant women with herpes zoster were identified, all of whom completed delivery. The average age of the participants was 31.4 ± 4.7 years. Nearly all (98.6%) experienced neuropathic pain. Seven women took oral acyclovir, two used Radix isatidis, and 37 did not receive medication. Ultimately, 38 women had vaginal deliveries, and 34 underwent cesarean sections. No adverse outcomes related to herpes zoster itself or its treatment were observed in either the mothers or their infants. Conclusion: Herpes zoster during pregnancy showed benign maternal-fetal outcomes regardless of antiviral use, supporting cautious management in this population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.