Evidence map›Paper›PMID 40200858›Full record

ReviewJournal of cosmetic dermatology2025

Lip Sonoanatomy and Relevance to Aesthetic Filler Injections: A Pictorial Review.

Wei-Ting Wu, Ke-Vin Chang, Ondřej Naňka, Hsiang-Chi Chang, Vincenzo Ricci, Kamal Mezian, Levent Özçakar

Abstract readReview
In one paragraph

Review in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wei-Ting WuDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital Bei-Hu Branch, Taipei, Taiwan.
Ke-Vin ChangDepartment of Physical Medicine and Rehabilitation, National Taiwan University Hospital Bei-Hu Branch, Taipei, Taiwan.ORCID https://orcid.org/0000-0002-7558-5651
Ondřej NaňkaInstitute of Anatomy, Charles University, First Faculty of Medicine, Prague, Czech Republic.
Hsiang-Chi ChangDepartment of Physical Medicine and Rehabilitation, Taipei Hospital Ministry of Health and Welfare, New Taipei City, Taiwan.
Vincenzo RicciPhysical and Rehabilitation Medicine Unit, Luigi Sacco University Hospital, ASST Fatebenefratelli-Sacco, Milan, Italy.
Kamal MezianDepartment of Rehabilitation Medicine, Charles University, First Faculty of Medicine and General University Hospital in Prague, Prague, Czech Republic.
Levent ÖzçakarDepartment of Physical and Rehabilitation Medicine, Hacettepe University Medical School, Ankara, Turkey.

Funding

Ministry of Science and Technology 109-2314-B-002-114-MY3Ministry of Science and Technology 111-2314-B-002-161Ministry of Science and Technology MOST 106-2314-B-002-180-MY3National Science and Technology, Taiwan NSTC 112-2314-B-002-134National Science and Technology, Taiwan NSTC 113-2314-B-002-208-MY2National Science and Technology, Taiwan NSTC 113-2314-B-002-209-MY2National Taiwan University Hospital, Bei-Hu BranchTaiwan Society of Ultrasound in Medicine
6 · The paper itself

Abstract

backgroundLips are central to facial aesthetics, influencing overall balance and harmony. Ultrasound has become a key tool for assessing lip musculature and neurovascular structures, particularly in aesthetic filler injections. By enhancing precision and safety, ultrasound is valuable in procedures addressing age-related lip changes, yet standardized scanning protocols remain underexplored.

aimsThis review examined lip anatomy, summarized ultrasound applications in aesthetic procedures, introduced a structured scanning protocol, and highlighted its role in guiding filler injections.

methodsA systematic search of PubMed, Scopus, Embase, and Web of Science was conducted up to August 1, 2024, using keywords related to ultrasound and lip anatomy. Studies involving human subjects or cadavers using ultrasound for lip assessment and injection guidance were included, whereas nonhuman studies, alternative imaging methods, and research unrelated to the lip region were excluded. Six studies met the criteria.

resultsUltrasound improves precision in lip injections by identifying key structures, including the superior and inferior labial arteries and the orbicularis oris muscle, reducing vascular risks. A structured scanning approach enhances procedural safety and efficacy.

conclusionsUltrasound is a valuable tool in aesthetic lip procedures, improving accuracy and minimizing complications. Further research is needed to refine protocols and establish ultrasound as a standard practice in lip augmentation.

Indexed as

Cosmetic TechniquesDermal FillersLipUltrasonography, InterventionalEstheticsHumansSkin AgingDermal Fillersaesthetic medicineinterventionlabial arterymouthultrasonography

Identifiers

PMID40200858
PMCPMC11979676

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.