ArticleAmerican journal of human biology : the official journal of the Human Biology Council2025
Delaying Motherhood-An Increasingly Common but Risky Trend in High-Income Countries.
Article in American journal of human biology : the official journal of the Human Biology Council, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- ASO Author Reflections: Can We Preserve Fertility without Compromising Oncologic Outcomes?: Preoperative Oncofertility for ER-Positive Breast Cancer.Annals of surgical oncology · 2026Article
- Maternal age as a driver of genome instability: mechanisms linking aneuploidy, mutagenesis and mitochondrial dysfunction.Archives of toxicology · 2026Review
- Adverse Maternal and Neonatal Outcomes Among Women of Advanced Maternal Age in a Tertiary-Care Setting in Bangladesh: A Cross-Sectional Study.Health science reports · 2026Article
- Positive association between fibrinogen-to-albumin ratio and preeclampsia risk in pregnant women of advanced maternal age: implications for clinical risk assessment.Frontiers in cardiovascular medicine · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesMaternal age at first birth is increasing in most high-income countries. The associations between advanced maternal age and perinatal complications, as well as newborn parameters, were analyzed using a dataset of 6831 singleton births among first-time mothers taking place in Vienna, Austria, between 2010 and 2019.
methodsIn this single-center medical records-based retrospective study, the following obstetrical parameters have been included: conception mode, preterm birth (< 37th gestational week), labor induction, planned or emergency cesarean sections, adverse child presentation, newborn size, and Apgar scores. The outcomes of first-time mothers older than 35 and 40 years, respectively, were compared to a reference group of first-time mothers aged between 20 and 34 years.
resultsFirst-time mothers aged 35 and older show a significantly (p < 0.009 resp. p < 0.001) higher risk of preterm births, with a 1.32-fold risk for women between 35 and 39 years and a 2.35-fold risk for women aged 40 and older. Maternal age is also significantly (p < 0.001) associated with an increased rate of medically induced labor, cesarean sections, and low-weight newborns (< 2500 g). In contrast, there was no significant difference in Apgar scores among the newborns of different maternal age groups.
conclusionsAdvanced maternal age at first birth is a relevant risk factor for certain obstetric and neonatal complications. Delaying motherhood is a risky trend.
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