Evidence map›Paper›PMID 40200820›Full record

ArticlePediatric transplantation2025

Management of Trichodysplasia Spinulosa in a Pediatric Kidney Transplant Patient With Topical Cidofovir and Oral Leflunomide.

Annika M Hansen, Sonia Mehra, Anneli R Bowen, Joseph Sherbotie, Sarah D Cipriano

Abstract readCase Reports
In one paragraph

Article in Pediatric transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Annika M HansenSpencer Fox Eccles School of Medicine, Salt Lake City, Utah, USA.ORCID 0000-0002-6455-5473
Sonia MehraDepartment of Pediatrics, University of Utah, Salt Lake City, Utah, USA.
Anneli R BowenDepartment of Dermatology, University of Utah, Salt Lake City, Utah, USA.
Joseph SherbotieDepartment of Pediatrics, University of Utah, Salt Lake City, Utah, USA.
Sarah D CiprianoDepartment of Dermatology, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0003-0888-1458

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis case report describes a 10-year-old male with a history of kidney transplantation who developed trichodysplasia spinulosa (TS), a rare skin disorder associated with immunosuppression.

methodsThe patient's condition, characterized by follicular papules and keratinous spines primarily on the face, was managed by a multidisciplinary team.

resultsTreatment involved reducing immunosuppression and administering topical cidofovir alongside oral leflunomide, leading to significant clinical improvement over several months.

conclusionsThis case adds to the literature of TS management and highlights the importance of multidisciplinary care as well as the challenges of treatment accessibility due to insurance limitations.

Indexed as

Antiviral AgentsCytosineImmunosuppressive AgentsIsoxazolesKidney TransplantationOrganophosphonatesPostoperative ComplicationsAdministration, OralAdministration, TopicalChildCidofovirHumansLeflunomideMaleAntiviral AgentsCidofovirCytosineImmunosuppressive AgentsIsoxazolesLeflunomideOrganophosphonatesimmunosuppressiontransplantviral

Identifiers

PMID40200820
PMCPMC11979675

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.