Evidence map›Paper›PMID 40200595›Full record

ArticleActa dermato-venereologica2025

Type 2 Diabetes Impacts the Efficacy of Syphilis Treatment and is a Risk Factor for Late Syphilis: A Retrospective Cohort Study.

Yijie Tang, Mengxiao Wu, Wenwen Xu, Jiajie Yu, Dandan Yang, Jiaqin Zhang, Lingyun Shen, Qinghui Xie, Qingqiong Luo

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Article in Acta dermato-venereologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yijie Tang *Department of Clinical Laboratory Medicine, Shanghai Skin disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Mengxiao Wu *Department of Biochemistry, School of Basic medical science, Fudan University, Shanghai, China.
Wenwen XuDepartment of Clinical Laboratory Medicine, Shanghai Skin disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Jiajie YuDepartment of Clinical Laboratory Medicine, Shanghai Skin disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Dandan YangDepartment of Clinical Laboratory Medicine, Shanghai Skin disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Jiaqin ZhangDepartment of Clinical Laboratory Medicine, Shanghai Skin disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Lingyun ShenDepartment of Clinical Laboratory Medicine, Shanghai Skin disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Qinghui XieDepartment of Clinical Laboratory Medicine, Shanghai Skin disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Qingqiong LuoDepartment of Clinical Laboratory Medicine, Shanghai Skin disease Hospital, School of Medicine, Tongji University, Shanghai, China. luoqingqiong2007@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the relationship between type 2 diabetes and late syphilis. A retrospective analysis was conducted, including 96 syphilis patients with type 2 diabetes and 122 matched non-diabetic syphilis controls. The development of late-stage syphilis and responses to initial treatment were monitored over a 2-year period. Stratified logistic regression was used to assess whether diabetes increased the risk of late syphilis. Differences in initial treatment responses between the 2 groups were evaluated using χ2 tests and Kaplan-Meier curves. The cohort study confirmed that the serological cure rate within 12 months was significantly lower in diabetic syphilis patients. Type 2 diabetes significantly impacts the efficacy of syphilis treatment and is a risk factor for late syphilis.

Indexed as

Anti-Bacterial AgentsDiabetes Mellitus, Type 2SyphilisAdultAgedChi-Square DistributionFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeAnti-Bacterial Agents

Identifiers

PMID40200595
PMCPMC11995729

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.