Evidence map›Paper›PMID 40200578›Full record

ArticleBiophysical journal2025

Modeling platelet P2Y

Keshav B Patel, Wolfgang Bergmeier, Aaron L Fogelson

Abstract read
In one paragraph

Article in Biophysical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Keshav B PatelDepartment of Mathematics, University of Utah, Salt Lake City, Utah.
Wolfgang BergmeierDepartment of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina; Blood Research Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Aaron L FogelsonDepartment of Mathematics, University of Utah, Salt Lake City, Utah; Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah. Electronic address: fogelson@math.utah.edu.

Funding

Small GTPases in the biology of platelets and megakaryocytesR35HL144976 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BERGMEIER, WOLFGANG · 2019 to 2025
$5.4M
An integrated computational and experimental approach to understanding the hemostatic response during treatment of bleedingR01HL151984 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI FOGELSON, AARON L, LEIDERMAN, KARIN · 2020 to 2023
$2.8M
NHLBI NIH HHS R01 HL151984NHLBI NIH HHS R35 HL144976
6 · The paper itself

Abstract

Through experimental studies, many details of the pathway of integrin α

Indexed as

Blood PlateletsIntegrinsModels, BiologicalReceptors, Purinergic P2Y1Receptors, Purinergic P2Y12Signal TransductionAdenosine DiphosphateHumansPlatelet AggregationPlatelet Glycoprotein GPIIb-IIIa Complexrap1 GTP-Binding ProteinsAdenosine DiphosphateIntegrinsPlatelet Glycoprotein GPIIb-IIIa Complexrap1 GTP-Binding ProteinsReceptors, Purinergic P2Y1Receptors, Purinergic P2Y12

Identifiers

PMID40200578
PMCPMC12242414

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.