Evidence map›Paper›PMID 40200369›Full record

ArticleMilitary Medical Research2025

Endovascular treatment for cerebral venous thrombosis: a multicenter study in China.

He-Tao Bian, Xia Wang, Gui-You Liu, Chen Zhou, Ran Meng, Lan Liu, Jian-Gang Duan, Feng Yan, Chuan-Hui Li, Min Li and 32 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Military Medical Research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Cerebral venous thrombosis: Current management, recent advances and future directions.International journal of stroke : official journal of the International Stroke Society · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

42 authors.

He-Tao Bian *Beijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China.
Xia Wang *The George Institute for Global Health, University of New South Wales, Sydney, 2000, Australia.
Gui-You LiuBeijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China.
Chen ZhouBeijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China.
Ran MengDepartment of Neurology, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
Lan LiuSchool of Statistics, University of Minnesota at Twin Cities, Minneapolis, MN, 55455, USA.
Jian-Gang DuanDepartment of Emergency, Xuanwu Hospital of Capital Medical University, Beijing, 100053, China.
Feng YanDepartment of Neurosurgery, Xuanwu Hospital of Capital Medical University, Beijing, 100053, China.
Chuan-Hui LiDepartment of Neurology and Stroke Center, Xuanwu Hospital of Capital Medical University, Beijing, 100053, China.
Min LiDepartment of Neurology, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.
Wen HuiDepartment of Science and Technology, West China Hospital of Sichuan University, Chengdu, 610041, China.
Xu-Xiang ZhangDepartment of Ophthalmology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.
Dong ZhaoDepartment of Center for Clinical and Epidemiologic Research, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100013, China.
Ya-Peng LiDepartment of Neurology, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450002, China.
Qi FangDepartment of Neurology, the First Affiliated Hospital of Soochow University, Suzhou, 215006, Jiangsu, China.
De-Zhi KangDepartment of Neurosurgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou, 350005, China.
Hong-Liang ZengDepartment of Neurology, Ganzhou People's Hospital, Ganzhou, 341000, Jiangxi, China.
Zhi-Jian LiangDepartment of Neurology, the First Affiliated Hospital of Guangxi Medical University, Xining, 530021, China.
Zheng-Hao ShiDepartment of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, 325000, Zhejiang, China.
Wei YueDepartment of Neurology, Tianjin Huanhu Hospital, Tianjin, 300350, China.
Qin-Jian SunDepartment of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, 250021, China.
Gui-Sheng ChenDepartment of Neurology, General Hospital of Ningxia Medical University, Yinchuan, 750001, China.
Jian-Long SongDepartment of Neurology, the First Affiliated Hospital of USTC, Hefei, 230001, China.
Zhong-Rui YanDepartment of Neurology, Jining First People's Hospital, Jining, 272113, Shandong, China.
Qiu-Hong JiDepartment of Neurology, Affiliated Hospital of Nantong University, Nantong, 226001, Jiangsu, China.
Kai-Jie WangDepartment of Neurology, Tangshan Gongren Hospital, Tangshan, 063099, Hebei, China.
Lu-Sha TongDepartment of Neurology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, 310009, China.
Xiao HuDepartment of Neurology, Guizhou Provincial People's Hospital, Guiyang, 550002, China.
Wen-Feng CaoDepartment of Neurology, Jiangxi Provincial People's Hospital, Nanchang, 330006, China.
Wei YanDepartment of Neurology, the First People's Hospital of Kashi, Kashi, 84000, Xinjiang, China.
Rui-Jiang GaoDepartment of Neurology, Inner Mongolia People's Hospital, Hohhot, 010010, China.
Qi LiDepartment of Neurology, the Second Affiliated Hospital of Anhui Medical University, Hefei, 230601, China.
Jian-Yi WangDepartment of Neurology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Yi LiuDepartment of Neurology, Shanxi Provincial People's Hospital, Taiyuan, 030012, China.
Bao-Jun WangDepartment of Neurology, Baotou Central Hospital Inner Mongolia, Baotou, 014040, Inner Mongolia Autonomous Region, China.
Xiao-Hua WangDepartment of Neurology, Qujing No. 1 Hospital, Qujing, 655000, Yunnan, China.
Sheng-Tao YaoDepartment of Neurology, Affiliated Hospital of Zunyi Medical University, Zunyi, 563099, Guizhou, China.
Ye LangDepartment of Neurology, Shengli Oilfield Central Hospital, Dongying, 257100, Shandong, China.
Hai-Peng LiDepartment of Neurology, the First People's Hospital of Chenzhou, Chenzhou, 424300, Hunan, China.
Craig S AndersonThe George Institute for Global Health, University of New South Wales, Sydney, 2000, Australia.
Xun-Ming JiBeijing Institute of Brain Disorders, Capital Medical University, Beijing, 100069, China. jixm@ccmu.edu.cn.ORCID http://orcid.org/0000-0002-0527-2852
RETAIN-CH Investigators and Coordinators

Funding

Innovative Research Group Project of the National Natural Science Foundation of China 82171278
6 · The paper itself

Abstract

backgroundEndovascular treatment (EVT) is gaining popularity for the management of severe forms of cerebral venous thrombosis (CVT), but the evidence supporting its efficacy and safety is limited.

methodsThis multicenter study included patients with CVT admitted to 104 hospitals in 31 provinces/cities in China between January 2018 and June 2022. Propensity score weighting models were used to adjust baseline confounding variables to determine the association of EVT on the primary outcome of good functional status, defined as score 0 - 1 on the modified Rankin Scale after hospital discharge.

resultsOf 3063 patients identified through hospital records searches, 2774 adults [age (42 ± 15.8) years, female 50.3%] fulfilled eligibility criteria and agreed to be included, of whom 449 (16.2%) received EVT and 2325 (83.8%) received standard care. There was no significant difference between the EVT group and the standard care group in terms of the possibility of good functional recovery [weighted risk ratio = 1.00, 95% confidence interval (CI) 0.96 - 1.03]. Similarly, there was no difference in the likelihood of death at hospital discharge (weighted risk ratio = 1.91, 95% CI 0.91 - 3.68). In subgroup analysis, the possibility of good functional recovery was lower in patients with intracerebral hemorrhage (weighted risk ratio = 0.88, 95% CI 0.79 - 0.98; P for interaction = 0.01) and seizures (weighted risk ratio = 0.86, 95% CI 0.76 - 0.95; P for interaction = 0.03).

conclusionIn this large nationwide study, EVT was not associated with improved functional outcomes compared to standard care in patients with CVT.

Indexed as

Endovascular ProceduresIntracranial ThrombosisVenous ThrombosisAdultChinaFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesCerebral venous thrombosis (CVT)EfficacyEndovascular treatment (EVT)SafetyStandard care

Identifiers

PMID40200369
PMCPMC11978133

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