Evidence map›Paper›PMID 40200263›Full record

ArticleBMC musculoskeletal disorders2025

Novel minimally invasive carpal tunnel release using a specialized surgical kit: a prospective multi-center case series.

Hsuan-Fu Chen, Shun-Min Chang, Chih-Ming Kao, Yu-Lin Chen, Li-Ting Kao, Ya-Chuan Hsu, Yin-Chih Fu, Yan-Hsiung Wang, Wen-Chih Liu, Tien-Ching Lee

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05067205 (Minimally Invasive Carpal Tunnel Decompression Using a Novel Ergonomic Releasing Instrument), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05067205 nacompletednot on this map

Minimally Invasive Carpal Tunnel Decompression Using a Novel Ergonomic Releasing Instrument

TypeinterventionalSponsorKaohsiung Medical UniversityRan2021 to 2022Enrolled41ConditionsCarpal Tunnel SyndromeArmsCarpal tunnel release surgery
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hsuan-Fu ChenDepartment of Orthopedics, Division of Sports Medicine and Orthopaedic Trauma, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No.100, Tzyou 1 Road, Kaohsiung, 80756, Taiwan.
Shun-Min ChangDepartment of Orthopedics, Division of Sports Medicine and Orthopaedic Trauma, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No.100, Tzyou 1 Road, Kaohsiung, 80756, Taiwan.
Chih-Ming KaoDepartment of Orthopedics, Division of Sports Medicine and Orthopaedic Trauma, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No.100, Tzyou 1 Road, Kaohsiung, 80756, Taiwan.
Yu-Lin ChenDepartment of Orthopedics, China Medical University Hospital, Taichung, 404327, Taiwan.
Li-Ting KaoOrthopaedic Research Center, College of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan.
Ya-Chuan HsuDepartment of Nursing, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 80756, Taiwan.
Yin-Chih FuDepartment of Orthopedics, Division of Sports Medicine and Orthopaedic Trauma, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No.100, Tzyou 1 Road, Kaohsiung, 80756, Taiwan.
Yan-Hsiung WangOrthopaedic Research Center, College of Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, 80708, Taiwan.
Wen-Chih LiuDepartment of Orthopedics, Division of Sports Medicine and Orthopaedic Trauma, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No.100, Tzyou 1 Road, Kaohsiung, 80756, Taiwan.
Tien-Ching LeeDepartment of Orthopedics, Division of Sports Medicine and Orthopaedic Trauma, Kaohsiung Medical University Hospital, Kaohsiung Medical University, No.100, Tzyou 1 Road, Kaohsiung, 80756, Taiwan. tn916943@gmail.com.

Funding

Kaohsiung Medical University KMU-TC112A02Ministry of Health and Welfare MOHW109-TDU-B-212-114006
6 · The paper itself

Abstract

backgroundCarpal tunnel syndrome (CTS) is the most common peripheral nerve compression neuropathy. While established surgical techniques have demonstrated reliable outcomes and safety profiles, innovations in minimally invasive approached continue to emerge. This study evaluates a novel minimally invasive surgical technique using a specialized instrument for carpal tunnel release.

methodsIn this prospective multi-center case series, 41 patients underwent minimally invasive carpal tunnel release using a novel surgical kit. Outcomes were assessed through Visual Analog Scale (VAS), Boston Carpal Tunnel Questionnaire (BCTQ), grip and pinch strength measurements, and nerve conduction velocity (NCV) testing at regular intervals over 24 weeks post-surgery.

resultsMean surgical time was 7.02 min. Significant improvements were observed in VAS scores (LS-Mean - 0.57, P < 0.0001) and BCTQ scores (Symptom Severity: LS-Mean - 2.62, P < 0.0001; Functional Status: LS-Mean - 1.20, P < 0.0001) by 24 weeks. Grip and pinch strengths showed significant improvement from 2 weeks post-surgery. Mean time to return to work was 18.2 days. NCV testing demonstrated significant improvements in both latency (LS-Mean - 0.57, P < 0.0001) and velocity (LS-Mean 5.79, P < 0.0001). One superficial infection and two cases of temporary numbness were reported, with no recurrent CTS observed.

conclusionsThis novel minimally invasive technique demonstrates promising clinical outcomes with shortened operative time, rapid symptom relief, and early functional recovery. While larger randomized studies are needed, these preliminary findings suggest this technique may be a valuable addition to current surgical options for CTS.

trial registrationClinicaltrials.gov, NCT05067205. Prospectively registered, date of first registration: 05/10/2021 ( https://clinicaltrials.gov/study/NCT05067205 ).

Indexed as

Carpal Tunnel SyndromeDecompression, SurgicalMinimally Invasive Surgical ProceduresAdultAgedFemaleHand StrengthHumansMaleMiddle AgedProspective StudiesTreatment OutcomeCarpal tunnel syndromeLocal anestheticMinimally invasive surgeryNerve conduction velocityPinch and grip strengths

Identifiers

PMID40200263
PMCPMC11980155

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.