ReviewBMC surgery2025
Radical cystectomy for bladder cancer in Sub-Saharan Africa: techniques, challenges, and survival outcomes: a comprehensive review.
Review in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Sexual life and intimate relationship experience among bladder cancer patients: a systematic review and qualitative meta-synthesis.Frontiers in public health · 2026Pooled it
- Impact of frailty on adverse outcomes after radical cystectomy: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radical cystectomy (RC) with urinary diversion remains the gold-standard treatment for muscle-invasive bladder cancer (MIBC), yet its implementation in Sub-Saharan Africa is hindered by late-stage presentation, limited surgical expertise, and inadequate perioperative care. These challenges contribute to higher morbidity and poorer survival outcomes compared to high-income regions. Additionally, the high prevalence of schistosomiasis-associated squamous cell carcinoma, disparities in multidisciplinary cancer care, and the burden of comorbidities further complicate treatment.This review examines RC techniques practiced in Africa, from open to minimally invasive approaches, assessing their feasibility within resource-limited settings. It explores challenges specific to the region, highlighting the impact of infrastructure gaps, limited access to neoadjuvant and adjuvant therapies, and variations in surgical training. Addressing these barriers requires urgent investment in oncology infrastructure, expanded access to multimodal therapy, and early detection strategies. Optimizing perioperative management and promoting cost-effective urinary diversion techniques are critical to improving bladder cancer outcomes in the region.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.