Evidence map›Paper›PMID 40199877›Full record

ArticleNature communications2025

Achieving flexible fairness metrics in federated medical imaging.

Huijun Xing, Rui Sun, Jinke Ren, Jun Wei, Chun-Mei Feng, Xuan Ding, Zilu Guo, Yu Wang, Yudong Hu, Wei Wei and 7 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Huijun Xing *Shenzhen Future Network of Intelligence Institute and Guangdong Provincial Key Laboratory of Future Networks of Intelligence, The Chinese University of Hong Kong (Shenzhen), Shenzhen, China.
Rui Sun *Shenzhen Future Network of Intelligence Institute and Guangdong Provincial Key Laboratory of Future Networks of Intelligence, The Chinese University of Hong Kong (Shenzhen), Shenzhen, China.ORCID http://orcid.org/0009-0007-1070-0712
Jinke Ren *Shenzhen Future Network of Intelligence Institute and Guangdong Provincial Key Laboratory of Future Networks of Intelligence, The Chinese University of Hong Kong (Shenzhen), Shenzhen, China.ORCID http://orcid.org/0000-0002-7409-6127
Jun Wei *Shenzhen Future Network of Intelligence Institute and Guangdong Provincial Key Laboratory of Future Networks of Intelligence, The Chinese University of Hong Kong (Shenzhen), Shenzhen, China.ORCID http://orcid.org/0000-0002-1263-5260
Chun-Mei FengInstitute of High Performance Computing, Agency for Science, Technology and Research, Singapore, Singapore.
Xuan DingDepartment of Statistics, Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, Guangdong, China.ORCID http://orcid.org/0009-0004-0318-2900
Zilu GuoShenzhen Future Network of Intelligence Institute and Guangdong Provincial Key Laboratory of Future Networks of Intelligence, The Chinese University of Hong Kong (Shenzhen), Shenzhen, China.ORCID http://orcid.org/0009-0000-4241-1682
Yu WangDepartment of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.ORCID http://orcid.org/0000-0001-6731-6518
Yudong HuAberdeen Institute of Data Science and Artificial Intelligence, South China Normal University, Foshan, Guangdong, China.ORCID http://orcid.org/0009-0001-9224-7152
Wei WeiDepartment of Gynecologic Oncology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, China.ORCID http://orcid.org/0000-0001-5929-7409
Xiaohua BanState Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, Guangdong, China.
Chuanlong XieDepartment of Statistics, Faculty of Arts and Sciences, Beijing Normal University, Zhuhai, Guangdong, China. clxie@bnu.edu.cn.ORCID http://orcid.org/0000-0003-4292-8782
Yu TanDepartment of Radiology, Guangdong Women and Children Hospital, Guangzhou, China.
Xian LiuRadiology Department, The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, China.
Shuguang CuiShenzhen Future Network of Intelligence Institute and Guangdong Provincial Key Laboratory of Future Networks of Intelligence, The Chinese University of Hong Kong (Shenzhen), Shenzhen, China.ORCID http://orcid.org/0000-0003-2608-775X
Xiaohui DuanDepartment of Radiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China. duanxh5@mail.sysu.edu.cn.ORCID http://orcid.org/0000-0002-2224-0887
Zhen LiShenzhen Future Network of Intelligence Institute and Guangdong Provincial Key Laboratory of Future Networks of Intelligence, The Chinese University of Hong Kong (Shenzhen), Shenzhen, China. lizhen@cuhk.edu.cn.ORCID http://orcid.org/0000-0002-7669-2686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid adoption of Artificial Intelligence (AI) in medical imaging raises fairness and privacy concerns across demographic groups, especially in diagnosis and treatment decisions. While federated learning (FL) offers decentralized privacy preservation, current frameworks often prioritize collaboration fairness over group fairness, risking healthcare disparities. Here we present FlexFair, an innovative FL framework designed to address both fairness and privacy challenges. FlexFair incorporates a flexible regularization term to facilitate the integration of multiple fairness criteria, including equal accuracy, demographic parity, and equal opportunity. Evaluated across four clinical applications (polyp segmentation, fundus vascular segmentation, cervical cancer segmentation, and skin disease diagnosis), FlexFair outperforms state-of-the-art methods in both fairness and accuracy. Moreover, we curate a multi-center dataset for cervical cancer segmentation that includes 678 patients from four hospitals. This diverse dataset allows for a more comprehensive analysis of model performance across different population groups, ensuring the findings are applicable to a broader range of patients.

Indexed as

Artificial IntelligenceDiagnostic ImagingFemaleHumansUterine Cervical Neoplasms

Identifiers

PMID40199877
PMCPMC11978761

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.