Evidence map›Paper›PMID 40199770›Full record

Trial reportClinical oral investigations2025

Comparative evaluation of efficacy of volume stable collagen matrix in interdental papilla reconstruction as compared to connective tissue graft in maxillary esthetic region: a randomized controlled clinical trial.

Geetanjali Sharma, Nishi Tanwar, Shikha Tewari, Ritika Arora

Abstract readRandomized Controlled TrialComparative Study
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Geetanjali SharmaDepartment of Periodontology, Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, Haryana, India.ORCID https://orcid.org/0000-0002-1688-6024
Nishi TanwarDepartment of Periodontology, Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, Haryana, India. nsh_tanwar@yahoo.co.in.ORCID https://orcid.org/0000-0001-9469-897X
Shikha TewariDepartment of Periodontology, Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, Haryana, India.ORCID https://orcid.org/0000-0002-2659-333X
Ritika AroraDepartment of Periodontology, Post Graduate Institute of Dental Sciences (PGIDS), Rohtak, Haryana, India.ORCID https://orcid.org/0000-0002-0740-1515

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe present study compared and evaluated the efficacy of volume-stable collagen matrix (VCMX) and subepithelial connective tissue graft (SCTG) in interdental papilla reconstruction. MATERIALS AND

methodsParticipants with class II interdental papilla loss (n = 36) were randomly assigned to test (VCMX) and control (SCTG) groups. Papillary height (PH), distance from the contact point to the tip of the papilla (CP-TP), keratinized tissue width (KTW), gingival tissue thickness (GT), and periodontal parameters were assessed at baseline,1, 3, and 6 months. Patient comfort and healing were also evaluated using a visual analog scale (VAS) at 1 week and healing index (HI) at 1,2 and 3 weeks post-operatively.

resultsOn intragroup comparison from baseline to 6 months, a statistically significant gain in papillary height, reduction in CP-TP, and an increase in KTW and GT was found in both groups (p = 0.001). Both groups found statistically significant improvement in the healing index from 1 to 3 weeks (p = 0.001). On intergroup comparison, VCMX showed comparable results to SCTG at 6 months, while VAS showed a statistically lower value in VCMX than SCTG (p = 0.044).

conclusionsVCMX and SCTG were found to be equally effective in interdental papilla reconstruction in terms of gain in papillary height and reduction in CP-TP distance. VCMX resulted in less post-operative pain compared to SCTG. CLINICAL RELEVANCE: VCMX may be preferred for interdental papilla reconstruction by clinicians and individuals due to its unlimited availability, which eliminates the need for an additional harvest site and reduces morbidity.

Indexed as

CollagenConnective TissueEsthetics, DentalGingival RecessionGingivoplastyMaxillaAdultFemaleHumansMaleMiddle AgedTreatment OutcomeCollagenCollagenConnective tissueEstheticsGingivaInterdental papillaRandomized controlled trial

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.