ReviewCurrent problems in pediatric and adolescent health care2025
Approach to the spectrum of infant non-IgE-mediated food allergy manifestations and physiologic infant behaviors.
Review in Current problems in pediatric and adolescent health care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Physiologic infant behaviors and symptoms of pathologic conditions such as gastroesophageal reflux disease, IgE-mediated food allergy, eosinophilic esophagitis, and other non-IgE-mediated food allergy (including food protein-induced allergic proctocolitis, acute and chronic forms of food protein-induced enterocolitis syndrome, and food protein-induced enteropathy) may have significant overlap, leading to diagnostic uncertainty for primary care physicians and pediatric subspecialists alike. Here we explore the clinical features of gastroesophageal reflux disease and IgE-mediated and non-IgE-mediated food allergy in infants, highlighting the considerable similarities in symptomology and difficulties in ascertaining an accurate diagnosis. Utilizing case studies, we discuss diagnostic and management pearls and review the ramifications of delayed diagnosis or misdiagnosis of infant food allergy for both infants and their caregivers.
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