Evidence map›Paper›PMID 40199577›Full record

ArticleSexually transmitted infections2025

Prevalence of chlamydia and gonorrhoea among Kenyan adolescents.

Hong-Ha M Truong, Beatrice Otieno, Kevin Kadede, Damaris Odeny, Maurice Opiyo, Marion Hewa, Fidel Opondo, Elsa Heylen, Sayo Amboka, Hanningtone Odhiambo and 5 more

Abstract read
In one paragraph

Article in Sexually transmitted infections, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Hong-Ha M TruongUniversity of California San Francisco, San Francisco, California, USA Hong-Ha.Truong@ucsf.edu.ORCID http://orcid.org/0009-0001-1283-5748
Beatrice OtienoUniversity of California Global Programs, Kisumu, Kenya.
Kevin KadedeKenya Medical Research Institute, Kisumu, Kenya.
Damaris OdenyKenya Medical Research Institute, Kisumu, Kenya.
Maurice OpiyoKenya Medical Research Institute, Kisumu, Kenya.
Marion HewaKenya Medical Research Institute, Kisumu, Kenya.
Fidel OpondoKenya Medical Research Institute, Kisumu, Kenya.
Elsa HeylenUniversity of California San Francisco, San Francisco, California, USA.
Sayo AmbokaKenya Medical Research Institute, Kisumu, Kenya.
Hanningtone OdhiamboKenya Medical Research Institute, Kisumu, Kenya.
David OgollaKenya Medical Research Institute, Kisumu, Kenya.
Lara MillerUniversity of California San Francisco, San Francisco, California, USA.
Craig R CohenUniversity of California San Francisco, San Francisco, California, USA.
Elizabeth A BukusiKenya Medical Research Institute, Nairobi, Kenya.
Maneno Yetu Study Team

Funding

In Our Own Words: Peer-to-Peer Messaging to Increase Uptake of HIV Prevention Strategies among Adolescents in KenyaR01HD094683 · NICHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI TRUONG, HONG-HA M · 2017 to 2021
$3.4M
NICHD NIH HHS R01 HD094683
6 · The paper itself

Abstract

objectivesSexually transmitted infections (STIs) diagnoses in Kenya are based on the identification of characteristic symptoms or syndromes without laboratory testing. Syndromic management likely underestimates STI prevalence due to undiagnosed asymptomatic infection. We assessed the prevalence and factors associated with chlamydia and gonorrhoea infections among adolescent boys and girls participating in

methodsAdolescents aged 15-19 years residing in informal settlements in Kisumu were eligible to participate in a cross-sectional survey. Participants were recruited using respondent-driven sampling. Urine specimens were tested using the Molecular Xpert CT/NG test. Associations were assessed by multivariate logistic regression.

resultsSTI testing was offered to 1238 adolescents who reported having sex and 1167 accepted. Of the 1159 adolescents who had interpretable STI test results, 53% were girls and 74% were 18-19 years old. STI prevalence was 9.6% overall and higher among girls than boys (12.5% vs 6.3%; p<0.001). Of 111 adolescents who tested positive, 96 had chlamydia, 9 had gonorrhoea, 6 had both chlamydia and gonorrhoea, and 73 reported never experiencing any STI symptoms. Girls were twice more likely than boys to test positive for an STI after controlling for other demographic characteristics, sexual behaviour and STI-related characteristics (aOR=2.01, 95% CI 1.25, 3.24).

conclusionsNearly 10% of adolescents were diagnosed with chlamydia or gonorrhoea. STI prevalence was two times higher among girls than boys. Two-thirds of adolescents with a positive STI test result did not report experiencing symptoms and thus would have been missed by syndromic management. Undiagnosed and untreated STIs can result in onward transmission and significantly impact their reproductive health. Our findings lend support for expanding STI testing services in resource-constrained settings and developing point-of-care diagnostic assays that are rapid, inexpensive and accurate to address the STI epidemic and reduce the risk of sequelae.

Indexed as

Chlamydia InfectionsGonorrheaAdolescentCross-Sectional StudiesFemaleHumansKenyaMalePrevalenceSexual BehaviorYoung AdultChlamydia InfectionsGonorrheaSYNDROMIC MANAGEMENT

Identifiers

PMID40199577
PMCPMC13242884

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.