Evidence map›Paper›PMID 40199514›Full record

GuidelineClinical and experimental otorhinolaryngology2025

Guidelines for the Treatment of Laryngeal Cancer from the Korean Society of Head and Neck Surgery.

Jeon Yeob Jang, Geun-Jeon Kim, Sang-Yeon Kim, Min-Su Kim, Dong Kun Lee, Minsu Kwon, Dongbin Ahn, Myung Jin Ban, Young Kang, Ho-Ryun Won and 29 more

Abstract readGuideline
PubMed Full text at PMC Publisher
In one paragraph

Guideline in Clinical and experimental otorhinolaryngology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

39 authors.

Jeon Yeob JangDepartment of Otorhinolaryngology-Head and Neck Surgery, Ajou University School of Medicine, Suwon, Korea.
Geun-Jeon KimDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Sang-Yeon KimDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Min-Su KimDepartment of Otorhinolaryngology-Head and Neck Surgery, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, Korea.
Dong Kun LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, Dong-A University College of Medicine, Busan, Korea.
Minsu KwonDepartment of Otorhinolaryngology-Head and Neck Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Dongbin AhnDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, Daegu, Korea.
Myung Jin BanDepartment of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Cheonan, Korea.
Young KangDepartment of Otorhinolaryngology-Head and Neck Surgery, ThanQ Seoul Center for Thyroid-Head and Neck Surgery and Medicine, Seoul, Korea.
Ho-Ryun WonDepartment of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Korea.
Jae Won ChangDepartment of Otorhinolaryngology-Head and Neck Surgery, Chungnam National University College of Medicine, Daejeon, Korea.
Dong Won LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, Daegu Catholic University School of Medicine, Daegu, Korea.
Ki Nam ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon, Korea.
Yeon Soo KimDepartment of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
Ah Ra JungDepartment of Otorhinolaryngology-Head and Neck Surgery, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.
Jungirl SeokDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Hye Ran LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, International St. Mary's Hospital, Catholic Kwandong University College of Medicine, Incheon, Korea.
Sung-Chan ShinDepartment of Otorhinolaryngology-Head and Neck Surgery, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Korea.
Chang Myeon SongDepartment of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine, Seoul, Korea.
Gil Joon LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, Daegu, Korea.
Jihye KwakDepartment of Otorhinolaryngology-Head and Neck Surgery, School of Medicine, Kyungpook National University, Daegu, Korea.
Soo Yeon JungDepartment of Otorhinolaryngology-Head and Neck Surgery, Ewha Womans University College of Medicine, Seoul, Korea.
Bo Hae KimDepartment of Otorhinolaryngology-Head and Neck Surgery, Dongguk University Ilsan Hospital, Goyang, Korea.
Dong-Hyun LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Nayeon ChoiDepartment of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Eun Kyung JungDepartment of Otorhinolaryngology-Head and Neck Surgery, Chonnam National University Hwasun Hospital, Chonnam National University Medical School, Hwasun, Korea.
Yong Tae HongDepartment of Otorhinolaryngology-Head and Neck Surgery, Jeonbuk National University Medical School, Jeonju, Korea.
Hyun-Bum KimDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Seung Hoon HanDepartment of Otorhinolaryngology-Head and Neck Surgery, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea.
Su Il KimDepartment of Otorhinolaryngology-Head and Neck Surgery, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University, Seoul, Korea.
Ji Won KimDepartment of Otorhinolaryngology-Head and Neck Surgery, Inha University College of Medicine, Incheon, Korea.
Yoon-Jong RyuDepartment of Otorhinolaryngology-Head and Neck Surgery, Kangwon National University School of Medicine, Chuncheon, Korea.
Heejin KimDepartment of Otorhinolaryngology-Head and Neck Surgery, Hallym University Sacred Heart Hospital, Hallym University College of Medicine, Anyang, Korea.
Sung Joon ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, Chung-Ang University Gwangmyeong Hospital, Chung-Ang University College of Medicine, Seoul, Korea.
Hanaro ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea.
Eun-Jae ChungDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Seung-Kuk BaekDepartment of Otorhinolaryngology-Head and Neck Surgery, Korea University College of Medicine, Seoul, Korea.
Jun-Ook ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Kwang-Jae ChoDepartment of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.

Funding

National Cancer Center NCC-2112570
6 · The paper itself

Abstract

objectivesEffective treatment of laryngeal cancer requires clinical decision-making that balances survival outcomes with the preservation of essential functions, such as voice and swallowing. This study, led by the Clinical Practice Guideline Committee of the Korean Society of Head and Neck Surgery, aims to establish evidence-based recommendations to guide surgeons in optimizing treatment decisions for patients with laryngeal cancer.

methodsA literature search was performed in the PubMed, Embase, Cochrane Library, and KoreaMed databases by a literature search expert and subsequently reviewed by a panel of 39 committee experts. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) method was employed to assess the quality of evidence and develop and report the recommendations. The strength of each recommendation reflects the guideline panel's confidence that the benefits of an intervention outweigh its risks for the target population. After drafting the guidelines, Delphi questionnaires were distributed to members of the Korean Society of Head and Neck Surgery and an external reviewer panel.

resultsIn total, 15 evidence-based recommendations are provided, addressing six critical aspects of laryngeal cancer treatment: early-stage treatment, treatment of locally advanced cancer, neck management, adjuvant therapy, swallowing rehabilitation, and salvage treatment for recurrent tumors.

conclusionThe guidelines provide evidence-based, validated recommendations to support clinicians in making optimal treatment decisions for laryngeal cancer.

Indexed as

GuidelinesLaryngeal CancerLaryngectomyNeck DissectionOrgan Preservation

Identifiers

PMID40199514
PMCPMC12146613

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.