Evidence map›Paper›PMID 40198444›Full record

ArticlePediatric surgery international2025

Development of a clinical prediction model for postoperative complications following tubularized incised plate urethroplasty: a multicenter study.

YiWei Fang, Dan Yang, Ning Sun, HongChen Song, WeiPing Zhang, YunMan Tang, LuGang Huang, Yi Yang, Min Chao, Hong Ma and 11 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

21 authors.

YiWei Fang *Department of Urology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing, 100045, China.
Dan Yang *Beijing New Century Children's Hospital, Beijing, 100045, China.
Ning SunChildren's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hospital of Beijing Children's Hospital, Urumqi, 830054, China.
HongChen SongChildren's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hospital of Beijing Children's Hospital, Urumqi, 830054, China. songhch1975@126.com.
WeiPing ZhangDepartment of Urology, National Center for Children's Health, Beijing Children's Hospital, Capital Medical University, Beijing, 100045, China.
YunMan TangSichuan Academy of Medical Sciences, Sichuan Provincial People's Hospital(SAMSPH), Chengdu, 610072, China.
LuGang HuangWest China Hospital of Sichuan University, Chengdu, 610044, China.
Yi YangShengjing Hospital of China Medical University, Shenyang, 110004, China.
Min ChaoAnhui Children's Hospital, Hefei, 230022, China.
Hong MaAffiliated Hospital of Zunyi Medical University (Guizhou Children's Hospital), Zunyi, 563003, China.
JingTi ZhangXi 'an Children's Hospital, Xi'an, 710002, China.
XuHui ZhangShanxi Children's Hospital, Taiyuan, 030006, China.
ShouLin LiShenzhen Children's Hospital, Shenzhen, 518034, China.
Ning LiTongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, 230022, China.
Chao ChenThe First Affiliated Hospital of Guangxi Medical University, Nanning, 530021, China.
DaWei HeChildren's Hospital of Chongqing Medical University, Chongqing, 400015, China.
WenBo WuChildren's Hospital of Jiangxi Province, Nanchang, 330006, China.
Hua XieShanghai Children's Hospital, Shanghai, 200062, China.
Yong GuanTianjin Children's Hospital, Tianjin, 300134, China.
Yanfang YangHenan Children's Hospital, Zhengzhou, 450018, China.
Jianguo ZhangDepartment of Pediatric Surgery, Inner Mongolia Maternal and Child Health Hospital, Inner Mongolia Autonomous Region, Hohhot, 010020, China. zjg3134@vip.163.com.

Funding

Key R&D Program of Xinjiang 2023B03018
6 · The paper itself

Abstract

purposeThis multicenter study aimed to identify risk factors for postoperative complications following tubularized incised plate urethroplasty (TIP) in hypospadias patients and develop a clinical prediction model.

methodsRetrospective data from 17 tertiary centers (2018-2021) were analyzed. INCLUSION CRITERIA: primary TIP surgery with complete anatomical and follow-up data. EXCLUSION CRITERIA: prior urethral surgery, genetic disorders, or incomplete records. Multivariate logistic regression identified independent predictors. A nomogram model was constructed and internally validated using bootstrapping (1000 resamples). Discrimination (AUC) and calibration (Hosmer-Lemeshow test) were assessed.

resultsAmong 493 patients (median follow-up: 42 months), the complication rate was 23.7% (117/493), including urethrocutaneous fistula (17.6%), stricture (6.5%), and diverticulum (2.8%). Independent predictors were: post-incision urethral plate width (OR: 0.01, 95% CI 0-0.05), glans width (OR: 0.81, 95% CI 0.66-0.98), and urethral defect length (OR: 1.47, 95% CI 1.00-2.16). The nomogram demonstrated moderate discrimination (AUC: 0.723, 95% CI 0.668-0.777) and good calibration (Hosmer-Lemeshow P = 0.382).

conclusionA clinical prediction model incorporating post-incision urethral plate width, glans width, and urethral defect length showed acceptable predictive accuracy for TIP complications.

Indexed as

HypospadiasPostoperative ComplicationsUrethraUrologic Surgical Procedures, MaleChildChild, PreschoolHumansInfantMaleNomogramsRetrospective StudiesRisk FactorsHypospadiasPostoperative complicationsPredictive modelTubularized incised plate urethroplasty (TIP)

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.