Evidence map›Paper›PMID 40198370›Full record

Trial reportInternational journal of colorectal disease2025

Short-term outcomes for intracorporeal vs. extracorporeal anastomosis in laparoscopic right hemicolectomy for colonic cancer-a prospective cohort study (ICEA-study).

Emilie Schultz Hougaard, Benedicte Schelde-Olesen, Issam Al-Najami, Thomas Buchbjerg, Benjamin Schnack Brandt Rasmussen, Lasse Bugge, Thomas Kolbro, Sören Möller, Mark Bremholm Ellebæk

Registry-linked trialAbstract readClinical TrialComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of colorectal disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05039762 (Intracorporeal vs. Extracorporeal Anastomosis in Patients Undergoing Laparoscopic Right Hemicolectomy for Colonic Cancer - A Prospective Cohort Study), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05039762 naunknown statusnot on this map

Intracorporeal vs. Extracorporeal Anastomosis in Patients Undergoing Laparoscopic Right Hemicolectomy for Colonic Cancer - A Prospective Cohort Study

TypeinterventionalSponsorUniversity of Southern DenmarkRan2020 to 2025Enrolled104ConditionsColon CancerArmsExtracorporeal anastomosis, Intracorporeal anastomosis
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Standardised Pfannenstiel versus supraumbilical muscle-sparing transverse extraction sites in colon cancer surgery: An IDEAL stage 4 report.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Emilie Schultz HougaardDepartment of Surgery, Odense University Hospital, Odense, Denmark. emilie.schultz.hougaard@rsyd.dk.ORCID http://orcid.org/0009-0004-8575-334X
Benedicte Schelde-OlesenDepartment of Surgery, Odense University Hospital, Odense, Denmark.
Issam Al-NajamiDepartment of Surgery, Odense University Hospital, Odense, Denmark.
Thomas BuchbjergDepartment of Surgery, Odense University Hospital, Odense, Denmark.
Benjamin Schnack Brandt RasmussenDepartment of Clinical Research, University of Southern Denmark, Odense, Denmark.
Lasse BuggeDepartment of Surgery, Odense University Hospital, Odense, Denmark.
Thomas KolbroDepartment of Surgery, Odense University Hospital, Odense, Denmark.
Sören MöllerOPEN, Odense University Hospital, Odense, Denmark.
Mark Bremholm EllebækDepartment of Surgery, Odense University Hospital, Odense, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study is to compare short-term outcomes and 1-year incisional hernia rates between intracorporeal anastomosis (IA) and extracorporeal anastomosis (EA) in laparoscopic right hemicolectomy for management of right-sided colonic cancer. The primary outcome was the complication rate assessed by the comprehensive complication index (CCI). Secondary outcomes included time to bowel movement, length of hospital stay, 30-day readmission rate, early warning scores, and 1-year incisional hernia rate.

methodThis was a single-center, prospective cohort study. Patients with right-sided colonic cancer eligible for laparoscopic surgery with primary anastomosis were consecutively included. Patients included in the first period underwent EA, while those in the second underwent IA. Clinical data were collected during the hospital admission up to 30 days postoperatively. Complications were evaluated by the CCI. A routine 1-year CT-scan was used to assess hernias.

resultsOne hundred three patients (51 in the EA and 52 in the IA groups) were included. Demographics were similar between the two groups. No significant difference in the CCI-score was found (EA: 17.9 (23.9) vs. IA: 15.0 (17.4), p = 0.85). The mean length of hospital stay was significantly shorter in the IA group (EA 6.6 days, IA 3.9 days, p = 0.02). The groups had no significant differences regarding other outcomes, including hernia rates (p = 0.12).

conclusionLaparoscopic right hemicolectomy with IA significantly reduced the length of hospital stay without increasing complication rates compared to EA.

trial registrationThe study is registered at ClinicalTrials.gov (NCT05039762).

Indexed as

ColectomyColonic NeoplasmsLaparoscopyAgedAnastomosis, SurgicalFemaleHumansIncisional HerniaLength of StayMaleMiddle AgedPostoperative ComplicationsProspective StudiesTime FactorsTreatment OutcomeColonic cancerExtracorporeal anastomosisIntracorporeal anastomosis

Identifiers

PMID40198370
PMCPMC11978703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.