Evidence map›Paper›PMID 40197959›Full record

Trial reportCoDAS2025

Immediate effects of photobiomodulation with low-level laser in women with no laryngeal or voice changes: preliminary results.

Viviane Souza Bicalho Bacelete, Elisa Meiti Ribeiro Lin Plec, Flávio Barbosa Nunes, Andréa Rodrigues Motta, Ana Cristina Côrtes Gama

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in CoDAS, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Viviane Souza Bicalho BaceletePrograma de Pós-graduação em Ciências Fonoaudiológicas, Faculdade de Medicina, Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG), Brasil.ORCID http://orcid.org/0000-0002-4483-4125
Elisa Meiti Ribeiro Lin PlecPrograma de Pós-graduação em Ciências Fonoaudiológicas, Faculdade de Medicina, Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG), Brasil.ORCID http://orcid.org/0000-0003-1070-1954
Flávio Barbosa NunesDepartamento de Oftalmologia e Otorrinolaringologia, Faculdade de Medicina, Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG), Brasil.ORCID http://orcid.org/0000-0002-4353-4331
Andréa Rodrigues MottaDepartamento de Fonoaudiologia, Faculdade de Medicina, Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG), Brasil.ORCID http://orcid.org/0000-0002-1582-3785
Ana Cristina Côrtes GamaDepartamento de Fonoaudiologia, Faculdade de Medicina, Universidade Federal de Minas Gerais - UFMG - Belo Horizonte (MG), Brasil.ORCID http://orcid.org/0000-0002-7814-5328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the safety and immediate effect of photobiomodulation of low-level laser in vocally healthy women.

methodsExperimental research in 36 vocally healthy women aged 18 to 45 years, with skin phototype I to III and body mass index below 25. Participants were randomized to form four groups: Group 1: placebo laser photobiomodulation followed by voiced tongue trill technique (VTTT); Group 2: 3 J infrared laser per point (total 21 J) followed by VTTT; Group: 3: 6 J infrared laser per point (total 42 J) followed by VTTT; and Group 4: 9 J infrared laser per point (total 63 J) followed by VTTT. The following outcomes were assessed: auditory-perceptual evaluation, acoustic analysis (jitter, shimmer, amplitude perturbation quotient [APQ], noise-to-harmonic ratio, period perturbation quotient, cepstral peak prominence, and cepstral peak prominence smoothed), and self-perceived phonatory effort. All participants' records were taken before and immediately after the experiments.

resultsThere was no significant difference in voice quality, acoustic parameters, or self-perceived phonatory discomfort between intervention moments in the placebo, VTTT + 3 J, and VTTT + 6 J groups in the intragroup comparison. G4 (VTTT + 9 J) decreased shimmer and APQ aperiodicity measures (respective p-values: 0.033; 0.044).

conclusionResults indicate aperiodicity measures improved with VTTT preceded by 9 J low-level laser application per point, commending this irradiation dosimetry as a possible energy for voice therapy in light-skinned and normal-BMI women. There was no evidence of worsened measures or in-creased discomfort with this resource, indicating it is safe for clinical practice.

Indexed as

Low-Level Light TherapyVoice QualityAdolescentAdultFemaleHumansLarynxMiddle AgedSpeech AcousticsYoung Adult

Identifiers

PMID40197959
PMCPMC11991720

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.