Evidence map›Paper›PMID 40197942›Full record

ArticleDental press journal of orthodontics2025

Changes in subgingival microflora in patients with fixed orthodontic appliances.

Adriana Arbutina, Irena Kuzmanović Radman, Mirjana Umićević-Davidović, Marijana Arapović-Savić, Aleksandra Đeri, Radmila Arbutina, Saša Marin, Renata Josipović, Nataša Trtić

Abstract read
In one paragraph

Article in Dental press journal of orthodontics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adriana ArbutinaUniversity of Banja Luka, Faculty of Medicine, Department of Orthodontics (Banja Luka, Bosnia and Herzegovina).ORCID http://orcid.org/0000-0001-9930-3367
Irena Kuzmanović RadmanUniversity of Banja Luka, Faculty of Medicine, Department of Dental Diseases (Banja Luka, Bosnia and Herzegovina).ORCID http://orcid.org/0009-0008-4635-7730
Mirjana Umićević-DavidovićUniversity of Banja Luka, Faculty of Medicine, Department of Orthodontics (Banja Luka, Bosnia and Herzegovina).ORCID http://orcid.org/0000-0001-8787-1682
Marijana Arapović-SavićUniversity of Banja Luka, Faculty of Medicine, Department of Orthodontics (Banja Luka, Bosnia and Herzegovina).ORCID http://orcid.org/0009-0003-6328-600X
Aleksandra ĐeriUniversity of Banja Luka, Faculty of Medicine, Department of Dental Diseases (Banja Luka, Bosnia and Herzegovina).ORCID http://orcid.org/0000-0002-7203-8994
Radmila ArbutinaUniversity of Banja Luka, Faculty of Medicine, Department of Dental Diseases (Banja Luka, Bosnia and Herzegovina).ORCID http://orcid.org/0000-0002-2903-4111
Saša MarinUniversity of Banja Luka, Faculty of Medicine, Department of Oral Surgery (Banja Luka, Bosnia and Herzegovina).ORCID http://orcid.org/0000-0002-9605-0293
Renata JosipovićUniversity of Banja Luka, Faculty of Medicine, Department of Dental Diseases (Banja Luka, Bosnia and Herzegovina).ORCID http://orcid.org/0009-0006-1562-3747
Nataša TrtićUniversity of Banja Luka, Faculty of Medicine, Department of Oral Medicine and Periodontology (Banja Luka, Bosnia and Herzegovina).ORCID http://orcid.org/0000-0002-4856-2075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionFixed orthodontic therapy is often accompanied by accumulation of plaque around the orthodontic brackets, which increases the number of periodontopathogenic bacteria.

objectiveThe objective of this study was to determine the changes in the subgingival microflora that occurred six months after the placement of a fixed orthodontic appliance.

methodsThe study included 30 patients aged 13 to 35 years, in whom samples of subgingival plaque were taken before and six months after the start of fixed orthodontic therapy from the disto-buccal subgingival space of the left upper (U1) and lower central incisors (L1), mesio-buccal subgingival space of left upper (U6) and lower (L6) first molars. Material samples were tested for the presence of the following bacteria: Tannarela forsythia, Treponema denticola, Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Prevotella intermedia, Prevotella nigrescens and Eikenella corrodens, using the PCR method.

resultsA significant increase of patients with presence of bacteria especially in the molar region was found: Tannarela forsythia (U6 T1 10%-T2 80%, L6 T1 16.67%-T2 80%), Porphyromonas gingivalis (U6 T1 60%-T2 90%, L6 T1 60%-T2 83.33%), Prevotella intermedia (U6 T1 23.33%-T2 73.33%, L6 T1 26.67%-T2 76.67%), Prevotella nigrescens (U6 T1 16.67%-T2 63.33%, L6 T1 23.33%-T2 73.33%) and Eikenella corrodens (U6 T1 26.67%-T2 63.33%, L6 T1 23.33%-T2 73.33%) six months after the placement of the fixed orthodontic appliance.

conclusionIn the initial phase of fixed orthodontic therapy, an increase in the number of patients with periodontopathogenic bacteria Tannarela forsythia, Treponema denticola, Porphyromonas gingivalis, Prevotella intermedia, Prevotella nigrescens and Eikenella corrodens was observed.

Indexed as

Dental PlaqueGingivaOrthodontic Appliances, FixedOrthodontic BracketsAdolescentAdultAggregatibacter actinomycetemcomitansEikenella corrodensFemaleHumansIncisorMaleMolarPorphyromonas gingivalisPrevotella intermediaPrevotella nigrescens

Identifiers

PMID40197942
PMCPMC11980638

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.